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Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.

Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

The circadian clock influences the behavior and regeneration of stem cells in the body.

New alopecia treatments aim for better results and fewer side effects.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

Combining specific inducers helps dermal papilla cells regain hair-forming ability.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Manipulating cell cleanup processes could help treat hair loss.

Erdr1 could be a new marker for diagnosing hair loss.

Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

Recent advances in hair loss treatments show significant progress.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.