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Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Some teenagers with anorexia nervosa have worse cognitive abilities, especially in visual and spatial tasks, and this is more common in those with a lower body weight.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Allopregnanolone changes gene expression in glioblastoma cells.

Autophagy changes the protein makeup of hair.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Gut microbes significantly affect brain steroid levels.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.