4 citations,
November 2015 in “Journal of Investigative Dermatology” Testosterone may worsen hair loss by affecting hair growth signals, while different prostaglandins can either hinder or promote hair growth.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
232 citations,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
170 citations,
September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
67 citations,
December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
49 citations,
January 2018 in “Theranostics” The new skin patch with human matrix and antibiotic improves wound healing.
49 citations,
April 2003 in “Biomaterials” Bismuth subgallate and borneol together improve skin wound healing better than when used separately or compared to other treatments.
46 citations,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
43 citations,
January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
35 citations,
October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
26 citations,
January 1994 in “Clinics in Dermatology” Artificial skin is improving wound healing and shows potential for treating different types of wounds.
23 citations,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
22 citations,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
17 citations,
January 2016 in “Dermatology research and practice” Emu oil may slow down skin healing but increases hair growth in burn wounds.
16 citations,
March 2008 in “Dermatologic Surgery” Hydrogen peroxide's effects on wound healing in hair transplants are unclear, and it may slow healing and increase scarring.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
6 citations,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
6 citations,
January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
November 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
June 2008 in “Dermatologic Surgery” Hydrogen peroxide may have both positive and negative effects on wound healing, and its safe concentration for hair transplant surgery is unclear.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
55 citations,
June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
49 citations,
February 2020 in “Scientific reports” The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
41 citations,
September 2005 in “Wound Repair and Regeneration” Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.