Wound Healing, Cutaneous Therapy, and Hair Growth

February 2008 in “ Medical & surgical dermatology ”

topical oxygen emulsion epithelialization hydrocolloids adipose-derived stem cells ADSCs Hic-5/ARA55 AP-1 subunits hair follicle regeneration grafted cells anti-TNF treatment prostaglandin metabolism lysophospholipid receptor agonists lysophospholipid receptor antagonists bFGF hypertrophic scarring TOE stem cells anti-TNF therapy basic fibroblast growth factor

TLDR Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.

The document summarizes research on wound healing and hair growth, including a study that found topical oxygen emulsion (TOE) accelerated epithelialization in wounds and burns, and another that identified risk factors for complications after skin biopsies. A consensus panel recommended dressings for various wound stages, but a systematic review showed limited evidence for modern dressings' superiority over traditional ones, except for hydrocolloids. Adipose-derived stem cells (ADSCs) were found to be promising for wound healing and photoaging. The document also covers the role of Hic-5/ARA55 in hair follicles, the regulation of AP-1 subunits in wound healing, hair follicle regeneration using grafted cells, and improved skin repair in diabetic mice through anti-TNF treatment. Additionally, it discusses a study on anti-TNF therapy for skin ulcers, prostaglandin metabolism in hair follicles, the potential of lysophospholipid receptor agonists/antagonists in wound healing, the inhibitory effects of bFGF on hypertrophic scarring, and a trial comparing moist and dry dressings in vascular surgery with no significant outcome differences.

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Wound Healing, Cutaneous Therapy, and Hair Growth

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