12 citations
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December 2021 in “Aging” This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.
6 citations
,
January 2015 in “Journal of regenerative medicine & tissue engineering” This review discusses the role of stem cells and tissue engineering in regeneration and transplantation, emphasizing the need for advanced technologies to improve treatments for injuries and disabilities, but reports no new results.
3 citations
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March 2019 in “Archives of Plastic Surgery” This study found that hair transplantation effectively corrected altered hairlines and scarring arising from midface-lifting surgery, achieving high patient and physician satisfaction scores without adverse events.
February 2026 in “International Journal of Molecular Sciences” In this study, Lrig1-positive stem cells in mouse hair follicles were found to be essential for sebaceous gland formation and maintenance, with their depletion causing a temporary loss of these glands and changes in cellular differentiation.
January 2026 in “Biomaterials Science” This research outlines the characteristics and potential applications of a GMP-compliant sodium polyphosphate formulation (Na-polyP-GMP) in cellular energy storage and ATP-dependent processes like skin regeneration and wound healing.
June 2025 in “Food Science & Nutrition” This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.
January 2024 in “Journal of developmental biology” In this study, researchers observed that abdominal wounds in laboratory rats healed faster, completing epithelialization in 20 days versus 30 days for back wounds, possibly due to a higher expression of skin stem cell marker genes in the abdominal area.
January 2024 in “Journal of cosmetic dermatology” This study found that long-hair follicular unit excision for hairline restoration resulted in high patient satisfaction, with a 93% graft survival rate and improved quality of life scores postoperatively.
28 citations
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April 2024 in “Immunity” In this study, researchers found that hair follicle stem cells activate an immune-modulatory program during wound healing, promoting Treg cell expansion and aiding skin repair, while deleting certain immune components impaired healing and increased inflammation in a mouse model.
22 citations
,
November 2016 in “International journal of molecular sciences” This study suggests that impaired VDR signaling in mice leads to dysregulated Ddit4 expression, impacting hair cycle progression and wound healing.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
June 2025 in “Cancer Management and Research” This study found that scalp cooling resulted in visible hair retention in 53% of breast cancer patients undergoing Epirubicin/Cyclophosphamide and Paclitaxel treatment, with factors like hair bulb diameter, shaft diameter, and anagen rate significantly predicting outcomes.
319 citations
,
November 2005 in “Proceedings of the National Academy of Sciences” This study suggests that hair follicle stem cells from transgenic mice can improve nerve regeneration and function, highlighting their potential as an autologous source for regenerative medicine.
1 citations
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December 2023 in “Life” This article discusses the potential role of telocytes in skin regeneration and the need to understand their interaction with platelet-rich plasma, reporting no new experimental results.
1 citations
,
February 2016 in “Cell Transplantation” In this study, researchers found that hair follicles and dermal fibroblasts, including dermal papilla cells, supported sustained hair growth in transplanted murine models, with RNA-seq analysis revealing active signaling pathways and gene expression patterns.
February 2026 in “Frontiers in Microbiology” This review examines current understanding of how skin microbiota interact with and influence wound healing, highlighting the roles of commensal microorganisms in inflammation resolution, tissue regeneration, and barrier restoration, and discusses potential microbiota-based therapies for improving wound management.
January 2026 in “Dermatologic Therapy” This review indicates that while microneedling shows potential for managing androgenetic alopecia, particularly in combination with other treatments, the existing evidence is of low to moderate quality, and more robust trials are needed to confirm its clinical efficacy and safety.
August 2025 in “Stem Cell Research & Therapy” This study found that exosomes from human umbilical cord mesenchymal stem cells significantly promoted hair follicle growth and enhanced the transition to the growth phase in a model of androgenetic alopecia, by enriching specific microRNAs that activate key pathways involved in hair regeneration.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This article explores the potential of Hair Booster by Dantura Botanics, a micronutrient formulation aimed at restoring the biochemical environment needed for hair regeneration, and describes clinical observations suggesting that significant scalp degeneration can be reversed when follicles receive adequate micronutrients, according to this study.
22 citations
,
May 2011 in “Molecular Biology of the Cell” In this study, gene inactivation in mouse hair follicle stem cells lacking ILK impaired wound healing by reducing their progeny’s contribution to the regenerating epidermis, but did not affect hair follicle regeneration.
1 citations
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July 2025 in “Stem Cell Research & Therapy” In this study, researchers evaluated hair follicle transplantation techniques and reported that challenges such as limited follicle supply and low follicle survival rates often limit patient satisfaction, but advances in regenerative medicine may offer promising new solutions.
This review explores plant-derived exosomes as promising alternatives to synthetic wound-healing agents due to their ability to regulate signaling pathways involved in skin repair, while also addressing challenges in their clinical application.
This review explores the potential of regenerative cosmetics, specifically engineered skin tissues, for rejuvenating aging skin, healing wounds, and restoring hair, offering promising alternatives to traditional dermocosmetic treatments by promoting collagen production, reducing wrinkles, and regenerating hair follicles.
June 2026 in “Frontiers in Cell and Developmental Biology” This review synthesizes the diverse roles of the transcription factor LHX2 in development, tissue maintenance, and injury repair across various organ systems, highlighting its potential therapeutic applications and significance in regenerative medicine, particularly in developmental disorders and tissue regeneration.
January 2026 in “Burns & Trauma” This study reported that NLRP3 plays complex roles in wound healing by initially promoting inflammation and delaying repair, but later enhancing structural restoration through distinct signaling pathways, highlighting its potential as a therapeutic target for controlling inflammation and regeneration phases.
24 citations
,
September 2014 in “PloS one” This study demonstrated that thyroid hormone receptors play a crucial role in hair growth and skin health, as mice lacking these receptors showed impaired hair cycling and wound healing.
18 citations
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November 2016 in “PeerJ” This study found that hair follicles can be used to generate pluripotent stem cells, which successfully differentiate into keratinocytes and may improve hair regeneration and grafting for medical applications.
May 2026 in “International Journal of Molecular Sciences” In this review, researchers explore the roles of lactoferrin in skin and hair health, highlighting its potential anti-inflammatory and regenerative benefits despite the lack of well-controlled clinical trials for hair-specific outcomes.
March 2026 in “Oxford Journal of Student Scholarship” Hair follicle stem cells can help treat hair loss and chronic ulcers, but more research is needed for other uses.
February 2026 in “Journal of Korea Society of Ingrielogy” This review discusses the potential immuno-regenerative effects of polydioxanone threads in hair loss treatment, focusing on tissue responses and immune modulation, but does not report clinical results.