3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
July 2019 in “Dermatology practical & conceptual” The study found that alopecia areata is strongly linked to autoimmune diseases and may indicate a genetic predisposition to such conditions.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
May 2021 in “British Journal of Dermatology” Different tiny organisms live in human hair follicles and can affect both health and skin conditions, including acne and hair loss.
38 citations,
August 2012 in “Biochemical and biophysical research communications” Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.
110 citations,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
June 2023 in “International journal of research in Ayurveda and pharmacy” Malatyadi tailam effectively improved hair fall, dryness, and thinness in a patient.
2 citations,
May 2023 in “International Journal of Molecular Sciences” Gene expression in hair follicles can help diagnose methamphetamine use disorder.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
13 citations,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
10 citations,
June 2017 in “Experimental Dermatology” New hair loss treatments have evolved from understanding hair biology and patient needs.
January 2015 in “Springer eBooks” Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
4 citations,
November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
19 citations,
October 1996 in “Dermatologic Clinics” Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.
1 citations,
August 2023 in “Composites Part B: Engineering” The new wound dressing helps heal burn wounds and regrow hair by releasing beneficial ions.
11 citations,
February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
62 citations,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
4 citations,
February 2016 in “Clinical Pharmacology & Therapeutics” Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
29 citations,
April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” ICAM-1 helps regulate hair growth cycles and skin remodeling.
3 citations,
March 2023 in “Scientific Reports” Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
March 2024 in “International Journal of Cosmetic Science” Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
January 2024 in “Frontiers for young minds” Alopecia is a condition causing hair loss that can impact looks and mental health.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
11 citations,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
5 citations,
February 2016 in “Genetic Testing and Molecular Biomarkers” Hair loss is significantly linked to lower levels of certain genes in hair follicles.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
55 citations,
November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.