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research Oral isotretinoin combined with topical clobetasol 0.05% and tacrolimus 0.1% for the treatment of frontal fibrosing alopecia: a randomized controlled trial
This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
research 179 Eyebrow Hair Transplantation in Frontal Fibrosing Alopecia: Warning About the Short- and Long-Term Results
This study reported that while eyebrow hair transplantation in patients with frontal fibrosing alopecia achieves satisfactory short-term results, most patients experience significant hair graft loss within 3-4 years.
research Dermpath Quiz: Which alopecia does the patient have?
This case study diagnosed a 60-year-old woman with frontal fibrosing alopecia after histopathological analysis showed characteristic scarring patterns in the hairline area.
research Real-life Data for Tenofovir Alafenamide Fumarate Treatment of Hepatitis B: the Pythagoras Cohort
This study found that tenofovir alafenamide fumarate (TAF) is an effective and safer alternative to tenofovir disoproxil fumarate (TDF) for chronic hepatitis B, with fewer long-term side effects like nephrotoxicity and decreased bone density.
research Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris
This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
research Safflower oil body nanoparticles deliver hFGF10 to hair follicles and reduce microinflammation to accelerate hair regeneration in androgenetic alopecia
In a mouse model of androgenetic alopecia, this study found that a safflower oil body nanoparticle loaded with human fibroblast growth factor 10 significantly improved hair regeneration and reduced associated microinflammation without significant toxicity.
research Outcomes of Anatomic Reconstruction of Gunshot-Inflicted Lower Face Defects by Free Osteoseptocutaneous Fibula Flap and Expanded or Nonexpanded Temporal Scalp Flap Combination in Males
This study reports that using a combined approach of free osteoseptocutaneous fibula flap and temporal artery-based scalp flap provided satisfactory aesthetic and functional outcomes in reconstructing gunshot-inflicted composite mandibular defects in males.
research Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia
This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
research Protein profiling of forehead epidermal corneocytes distinguishes frontal fibrosing from androgenetic alopecia
This study found that patients with frontal fibrosing alopecia showed significant alterations in protein expression in forehead corneocytes, suggesting the condition may have systemic implications beyond the scalp.
research Hair Growth Regulation by Fibroblast Growth Factor 12 (FGF12)
In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.
research Characterizing the cellular diversity and molecular signatures within the hair follicle dermal stem cell lineage
This study identifies unique gene expression patterns in specialized fibroblasts within adult hair follicles, which advances understanding of their role in tissue regeneration.
research Stability Evaluation of Minoxidil in FOAMIL Form Base with Bracketing Study Design
This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
research Immunohistochemical localization of fibroblast growth factor 18 in hair follicles of healthy beagle dogs
This study identified fibroblast growth factor 18 in various components of canine hair follicles and other tissues, but found no significant differences in its presence across seasons, body regions, or sexes in beagle dogs.
research Treatment of frontal fibrosing alopecia and lichen planopilaris
This article includes no new results; it discusses ongoing treatment approaches for frontal fibrosing alopecia and lichen planopilaris.
research The clinical features and histopathologic patterns of folliculotropic mycosis fungoides in a series of 38 cases
This study describes the diverse histopathological patterns and clinical features observed in patients with folliculotropic mycosis fungoides, emphasizing the importance of accurate recognition to avoid diagnostic errors.
research Frontal fibrosing alopecia associated with cutaneous lichen planus in a premenopausal woman
This case report describes the first known instance of fibrosing alopecia associated with cutaneous lichen planus, suggesting fibrosing alopecia may be a variant of lichen planopilaris.
research Yin and yang of hair cells
This study observed that activin A and its antagonist follistatin influence the differentiation of inner ear hair cells by regulating the expression of the transcription factor ATOH1.
research Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats
This study demonstrated that FGF5s acts as an inhibitor of FGF5 in regulating hair growth cycles in cashmere goat dermal papilla cells.
research Reply to «Facial Papules in Frontal Fibrosing Alopecia: Good Response to Isotretinoin»
Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.
research Frontal fibrosing alopecia after antiandrogen hormonal therapy in a male patient
A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
research Alopecia frontal fibrosante en el varón: presentación de 12 casos y revisión de la literatura
This study found that men with frontal fibrosing alopecia were more likely to have facial papules, androgenetic alopecia, and body hair loss compared to women, with the average patient age being higher than in other series, potentially explaining these differences.
research Evaluation of Comprehensive Hormonal and Growth Factor Biomarker Panel in Female Pattern Hair Loss
This study found that women with female pattern hair loss exhibited hormonal imbalances, with the Free Androgen Index being a particularly effective diagnostic marker.
research Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
This review suggests that excessive facial photoprotection could play a role in frontal fibrosing alopecia through a disturbance in immunological balance via the aryl hydrocarbon receptor-kynurenine pathway.
research Facing up to the Liabilities of Non-profit Enterprise: A Strategy to Minimise and Finance Liabilities
This review discusses the use of follicular unit extraction for hair restoration, particularly body hair transplantation, and highlights its potential as an alternative donor source in advanced baldness cases, but reports no new clinical findings.
research Frontal Fibrosing Alopecia in Men: A Review of the Literature
According to this review, frontal fibrosing alopecia in men exhibits unique clinical features and is often misdiagnosed, underscoring the need for validated diagnostic criteria and treatment evaluation.
research Nail involvement in frontal fibrosing alopecia
This case report suggests that frontal fibrosing alopecia with nail involvement may be associated with lichen planus and improved with oral dutasteride due to an inflammatory reaction related to androgenetic alopecia.
research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection
This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.
research GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.