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This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.

Laser Lax is a new tool that measures scalp looseness accurately and comfortably.

This study found that treatment improved symptoms and stopped disease progression for 75% of lichen planopilaris patients whose follow-up data were available.

The authors concluded that Hispanic/Latino ethnicity, facial papules, and premenopausal status in patients with frontal fibrosing alopecia may indicate a susceptibility to more severe disease, potentially necessitating early treatment.

In a study reviewing 291 patients with lichen planopilaris, findings revealed that women were more commonly affected than men, cyclosporine and methotrexate were most effective in achieving remission, and 5-alpha reductase inhibitors and systemic retinoids were particularly beneficial for frontal fibrosing alopecia.

This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.

This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.

This study is the first to report that apremilast may be effective in treating refractory lichen planopilaris and frontal fibrosing alopecia, though some patients experienced adverse effects leading to discontinuation.

This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.

This study found that NIMP-R14-conjugated nanoparticles, loaded with roflumilast, effectively targeted neutrophils to reduce inflammation and improve symptoms in a mouse model of psoriasiform dermatitis, suggesting potential for targeted therapy in autoimmune skin diseases.

This study found that adding low-dose oral minoxidil to standard treatment for lichen planopilaris was safe but did not significantly improve hair density or thickness, although minor hair regrowth was observed in some scarring areas.

This article outlines the clinical and histological features of milia grouped in plaques on a 59-year-old woman's face but reports no new research findings.

This review discusses the clinical and histopathologic features of pediatric lichen planopilaris and reports therapeutic responses to various treatments; the condition should be considered in cases of patchy hair loss in children.

In this case report, a 65-year-old woman with lichen planopilaris achieved stabilization of her condition through early recognition and systemic corticosteroid therapy, emphasizing the critical role of coordinated management between primary care and dermatology.

Patients with Lichen Planopilaris are more likely to have rosacea and skin cancer but less likely to have congestive heart failure, stroke, and glaucoma.

This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.

This report diagnosed a 68-year-old man with comedonal folliculotropic mycosis fungoides based on clinical and histopathological findings, and found pegylated interferon alpha-2a with isotretinoin beneficial in reducing skin lesions.

This systematic review found that low-level light/laser therapy showed a positive effect in treating male and female pattern hair loss without side effects, as reported by all analyzed randomized controlled trials.

This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

This study introduced a single-stage network using large kernel attention that effectively restores high-resolution images by capturing both global and local details, reducing parameters and improving processing speed.

This study suggests that although data on JAK inhibitors for treating LPP and FFA is mainly from retrospective studies and case reports, these inhibitors may offer a new treatment option, particularly for challenging cases.

In this self-controlled comparative study of 16 women with Female Pattern Hair Loss, MMP® with Minoxidil showed a better response in the parietal-vertex regions in less advanced cases compared to standard Minoxidil treatment, though overall effectiveness was similar.

The study found that combining a 655nm low-level laser helmet with 2% minoxidil resulted in better improvement in hair diameter and intermediate hair enlargement at the midscalp among Chinese women with FPHL.

In this study, FAPD was characterized in a Chinese population by perifollicular mast cell infiltration, suggesting young individuals may be at higher risk than previously thought.

This review discusses the applications of confocal laser scanning microscopy in visualizing fluorescent compounds within the skin, noting its potential for tracking drug carriers and enhancing penetration studies, but reports no new results.

This review found that antimalarial agents were more effective than steroids for Lichen planopilaris, while finasteride and dutasteride showed favorable impacts on frontal fibrosing alopecia, despite heterogeneous study quality.

This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.

This source describes the first successful use of a deslorelin acetate implant to treat alopecia X in a neutered female dog, achieving profuse hair regrowth in 9 months, suggesting an uncomplicated and cost-effective alternative after melatonin failure.