Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases

    December 2015 in “ TURKDERM
    Deren Özcan, Deniz Seçkin, A. Tülin Güleç, Özlem Özen
    TLDR Lichen planopilaris can be accurately diagnosed and effectively treated.
    The study retrospectively reviewed 25 patients diagnosed with lichen planopilaris (LPP) between 2006 and 2012, with 18 females and 7 males, and a mean age of 49.8 years. Clinical findings included follicular hyperkeratosis (92%), perifollicular erythema (48%), and positive hair-pull test (44%). Histopathological findings showed follicular vacuolar and lichenoid degeneration (88%). Treatment with corticosteroids, minoxidil, tetracycline, cyclosporine A, and hydroxychloroquine, either alone or in combination, was administered to 23 patients. Among 16 patients with follow-up data, 75% experienced reduced symptoms and/or signs and halted disease progression. The study concluded that LPP could be accurately diagnosed and effectively managed with appropriate treatment.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 47 results

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community What is this pigmentation around my follicles?

      in Chat  29 upvotes 1 month ago
      The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

      community Joined the Dutasteride Master Race

      in Finasteride/Dutasteride  305 upvotes 1 day ago
      Dutasteride and finasteride are discussed for hair loss treatment, with users sharing experiences and debating their effectiveness and side effects. Celebrities are noted as common users, and there is debate over which treatment is superior.

    Similar Research

    6 / 1000+ results