Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases
December 2015
in “
TURKDERM
”
New to Minoxidil? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that treatment improved symptoms and stopped disease progression for 75% of lichen planopilaris patients whose follow-up data were available.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study retrospectively reviewed 25 patients diagnosed with lichen planopilaris (LPP) between 2006 and 2012, with 18 females and 7 males, and a mean age of 49.8 years. Clinical findings included follicular hyperkeratosis (92%), perifollicular erythema (48%), and positive hair-pull test (44%). Histopathological findings showed follicular vacuolar and lichenoid degeneration (88%). Treatment with corticosteroids, minoxidil, tetracycline, cyclosporine A, and hydroxychloroquine, either alone or in combination, was administered to 23 patients. Among 16 patients with follow-up data, 75% experienced reduced symptoms and/or signs and halted disease progression. The study concluded that LPP could be accurately diagnosed and effectively managed with appropriate treatment.
