Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases

December 2015 in “ TURKDERM ”

Deren Özcan, Deniz Seçkin, A. Tülin Güleç, Özlem Özen

lichen planopilaris follicular hyperkeratosis perifollicular erythema hair-pull test follicular vacuolar degeneration lichenoid degeneration corticosteroids minoxidil tetracycline cyclosporine A hydroxychloroquine Rogaine

TLDR Lichen planopilaris can be accurately diagnosed and effectively treated.

The study retrospectively reviewed 25 patients diagnosed with lichen planopilaris (LPP) between 2006 and 2012, with 18 females and 7 males, and a mean age of 49.8 years. Clinical findings included follicular hyperkeratosis (92%), perifollicular erythema (48%), and positive hair-pull test (44%). Histopathological findings showed follicular vacuolar and lichenoid degeneration (88%). Treatment with corticosteroids, minoxidil, tetracycline, cyclosporine A, and hydroxychloroquine, either alone or in combination, was administered to 23 patients. Among 16 patients with follow-up data, 75% experienced reduced symptoms and/or signs and halted disease progression. The study concluded that LPP could be accurately diagnosed and effectively managed with appropriate treatment.

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