Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases

The study retrospectively reviewed 25 patients diagnosed with lichen planopilaris (LPP) between 2006 and 2012, with 18 females and 7 males, and a mean age of 49.8 years. Clinical findings included follicular hyperkeratosis (92%), perifollicular erythema (48%), and positive hair-pull test (44%). Histopathological findings showed follicular vacuolar and lichenoid degeneration (88%). Treatment with corticosteroids, minoxidil, tetracycline, cyclosporine A, and hydroxychloroquine, either alone or in combination, was administered to 23 patients. Among 16 patients with follow-up data, 75% experienced reduced symptoms and/or signs and halted disease progression. The study concluded that LPP could be accurately diagnosed and effectively managed with appropriate treatment.