March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
November 2024 in “Stem Cell Research & Therapy” A new method improves the isolation of hair follicle cells for better hair growth research.
This study reports that mesenchymal stromal cell-derived extracellular vesicle injections led to complete hair regrowth in a patient with persistent chemotherapy-induced alopecia.
January 2019 in “Georg Thieme Verlag eBooks” This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.
November 2018 in “Springer eBooks” The document concludes that hair transplant methods are often selected for provider convenience over patient benefit, highlighting the need for less invasive techniques and careful physician involvement for better results.
July 2018 in “Journal of Oral and Maxillofacial Surgery” This review chronicles the history and evolution of oral and maxillofacial surgery over the past century, emphasizing advancements in office-based practice and the impact of technological and clinical innovations.
January 2016 in “Springer eBooks” The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
January 2016 in “Georg Thieme Verlag eBooks” Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.
January 2011 in “Springer eBooks” Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.
January 2010 in “Elsevier eBooks” Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.
October 2022 in “Our Dermatology Online” In this study, researchers compared the effectiveness of a tonic containing Capixyl, Procapil, and rosemary extract with 2% minoxidil in reducing hair loss and promoting hair growth in male participants over a 24-week period.
480 citations
,
August 2014 in “Nature Biotechnology” This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.
211 citations
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November 2018 in “Nature Cell Biology” This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.
69 citations
,
December 2016 in “Facial plastic surgery” This review discusses the anatomical and histological characteristics of facial fat compartments and reports no new clinical results, emphasizing a need for further research on their role in facial aging.
24 citations
,
November 2023 in “Nature” In this study, researchers demonstrated that the expression of the oncogene SmoM2 leads to basal cell carcinoma in the ear epidermis of mice but not in the back skin, with differences in susceptibility linked to the composition of the extracellular matrix.
9 citations
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May 2025 in “Stem Cell Research & Therapy” This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.
8 citations
,
October 2021 in “Experimental cell research” This study found that macrophage-engineered extracellular vesicle mimetics may promote hair regrowth, presenting a potential alternative to extracellular vesicles for overcoming clinical production challenges.
7 citations
,
May 2025 in “Stem Cell Research & Therapy” This review compiles EV proteomics data and reports that while MSC-derived EVs show promise in skin therapeutics, variability in protein cargo highlights the need for standardized methodologies in understanding process impacts.
1 citations
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January 2019 in “Elsevier eBooks” This chapter reviews the use of electrospun matrices in creating tissue-engineered skin substitutes and reports no new clinical results; it emphasizes the need for a cell-friendly microenvironment.
1 citations
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September 2018 in “Australasian Journal of Dermatology” In this report, a 2-year-old male with GAPO syndrome exhibited androgenetic-like alopecia with normal testosterone levels and telogen hair loss, which are novel findings for this condition.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
22 citations
,
August 2015 in “PloS one” This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.
20 citations
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February 2018 in “Cell transplantation” This study found that the water extract of Cinnamomum osmophloeum Kanehira leaves enhanced hair growth in vitro and in a mouse model, suggesting potential use for treating hair loss.
August 2021 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study found that using natural polyphenol cross-linkers like tannic acid and green tea extract during perm treatments improved perming efficiency, wave maintenance, and hair protection compared to a control group.
January 2015 in “Springer eBooks” This chapter reviews the potential of adipose-derived stem cells for skin aging and hair loss treatments but reports no new experimental results; the authors highlight these stem cells as a promising regenerative resource.
10 citations
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January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
1 citations
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March 2022 in “Daehanhanuihakoeji” In this study, Artemisia sieversiana extract was found to safely promote hair follicle dermal papilla cell growth and inhibit hair loss through anti-androgen, anti-inflammatory, and antioxidant effects at a cellular level.
Surgeons should evaluate new technologies critically, offer a range of services including non-surgical options, and be aware of marketing influences to meet patient needs and maintain a successful practice.
238 citations
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March 2013 in “Development” This study found that adipocytes play a crucial role in skin wound healing by facilitating fibroblast recruitment and dermal reconstruction during the healing process.
184 citations
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October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.