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This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.

This study found that epidermal growth factor decreased hair growth rate and altered hair characteristics in neonatal mice, with some effects persisting into subsequent hair generations.

This study reports that high-purity rHFSCs with strong proliferation and high VEGF165 expression can be efficiently obtained, facilitating tissue engineering applications like artificial hair follicles and skin construction.

In this study, researchers found that the FOS gene may play a significant role in promoting hair follicle development in Tan sheep between birth and the Er-mao period.

In this report, two cases of non-small cell lung cancer treated with gefitinib showed unexpected hair growth, suggesting a potential new application of EGFR-TKIs for alopecia.

This study found that OVOL1-regulated genes, particularly Fst and SFRP1, significantly affect the hair-inducing capacity of neonatal mouse dermal cells.

In this study, the researchers identified the SPEF2 and PRLR genes as potential candidates associated with feather rate phenotypes in Shouguang chickens through combined genome-wide association and differential expression analyses.

This study found that transgenic mice overexpressing HGF/SF are more susceptible to UVA-induced melanoma, with melanin in the papillary dermis interacting with UVA to induce melanoma.

This study found that the expression of IGF-1 receptor was significantly reduced in women with female androgenetic alopecia compared to healthy controls.

This study found that ginsenoside F2 may suppress hair cell apoptosis and improve hair growth outcomes in a DHT-induced hair loss model more effectively than finasteride.

In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.

This study found that a new hydrogel formulation of basic fibroblast growth factor showed promise in promoting hair regrowth and reducing inflammation in testosterone-treated mice.

This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.

Nelfb is essential for dermal fat development and survival.

Folliculin slows hair growth, and blocking it might help treat hair loss.

This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.

This study found that the IGF2 gene Apa1 A820G polymorphism is associated with an increased risk of developing PCOS in the studied population.

This study found that the controlled release of specific growth factors from biodegradable hydrogels significantly enhanced hair follicle growth and hair shaft length in mice compared to growth factors in solution.

This study investigated the gene Col19a1, finding its expression is specific to certain cells during hair follicle development in mice, suggesting its potential role in hair follicle morphogenesis.

This study found that growth factor concentrate provides quicker improvements for patterned hair loss, but platelet-rich plasma offers more sustained benefits after treatment.

In this study, the combination of keratin-gelatin from poultry feathers promoted early acceptance and viability of full-thickness skin mesh grafts in experimental dogs compared to other treatments.

This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.

This study found that patient-derived HGF significantly accelerates wound healing in diabetic mice, particularly improving skin structure and flexibility, and rHGF plays a key role in boosting hair growth.

This study found that NFI-C plays a crucial role in the transition from the telogen to anagen phase of the hair follicle cycle, affecting hair growth initiation in mice.

This study observed that antisense oligonucleotides targeting FGFR-1 increased cellular activity in hair follicle cultures from mice, suggesting potential clinical utility for treating baldness.

This study found that the miR-140-y-TCF4 axis regulates the proliferation of goose embryonic dermal fibroblast cells by affecting the Wnt signaling pathway, highlighting its role as a dynamic regulator during skin and feather follicle development.

This case report describes a 16-year-old girl with severe generalized gingival fibromatosis and hypertrichosis, who underwent successful treatment through gingivectomy, with uneventful healing observed over an eight-month follow-up.

This study demonstrates that combining gene expression data with a random forest algorithm provides highly accurate diagnosis of childhood growth hormone deficiency, showing potential utility in distinguishing it from non-GHD short stature.

This study identified significant genetic associations with frontal fibrosing alopecia at four genomic loci, suggesting it is a genetically predisposed immuno-inflammatory disorder influenced by the HLA-B*07: 02 allele.