The Influence of pdHGF on Wound Healing

    January 2012 in “ RWTH Publications (RWTH Aachen) ”
    Britta Anna Kühlmann, Norbert Pallua
    TLDR pdHGF speeds up wound healing and hair growth.
    The study investigated the effects of patient-derived HGF (pdHGF) on wound healing and hair growth using diabetic and C57/BL6 mouse models. It found that pdHGF significantly accelerated wound healing, particularly between days 13 to 16, and improved skin structure by reducing collagen rigidity. This suggests pdHGF could help reconstruct physiological skin structure and function. The study also indicated that lower HGF concentrations could effectively treat chronic wounds. Additionally, recombinant HGF (rHGF) was shown to accelerate hair growth, suggesting potential new treatments for hair diseases.
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