32 citations,
January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
14 citations,
January 2019 in “Journal of Natural Medicines” Chaga mushrooms contain compounds that may promote hair growth better than common treatments.
7 citations,
March 2007 in “International Journal of Dermatology” Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
10 citations,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
47 citations,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
47 citations,
June 2017 in “The FEBS journal” Disabling the FGF5 gene in sheep leads to longer wool.
11 citations,
October 2014 in “Gene” Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.
27 citations,
February 2017 in “Clinical, Cosmetic and Investigational Dermatology” New compounds were found to help increase hair growth and decrease hair loss.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
6 citations,
September 2019 in “Archives of Dermatological Research” Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
112 citations,
January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
7 citations,
June 2017 in “Gene” Overexpression of FGF5s makes Chinese Merino sheep grow longer and heavier wool.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
44 citations,
September 2015 in “Annals of Oncology” Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
1 citations,
June 2021 in “Journal of pharmacopuncture” CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
100 citations,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
163 citations,
October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
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45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
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January 2022 in “Molecules” Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.
34 citations,
January 2018 in “International Journal of Dermatology” Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
27 citations,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.