6 citations
,
July 2004 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This case report documents two postmenopausal women with frontal fibrosing alopecia whose hair loss stabilized after treatment with topical corticosteroids, one also using minoxidil.
December 2025 in “Actas Dermo-Sifiliográficas” This consensus from 22 Spanish dermatologists recommends using a multimodal therapy starting with oral dutasteride, combined with topical and/or intralesional agents, and adding hydroxychloroquine if inflammation persists, to manage frontal fibrosing alopecia due to its irreversible hair loss and lack of specific approved treatments.
This study examined epidemiological data on patients with frontal fibrosing alopecia in Greece and found demographic patterns consistent with international studies.
4 citations
,
December 2020 This case report describes a woman with frontal fibrosing alopecia who did not improve with hydroxychloroquine and topical minoxidil but achieved clinical stabilization with methotrexate monotherapy.
1 citations
,
July 2018 in “Elsevier eBooks” This review discusses the pathogenesis and clinical features of androgenetic alopecia, highlighting potential links to fibrosing alopecia and suggesting the need for combined therapeutic approaches; it reports no new clinical results.
January 2024 in “JEADV clinical practice” This study reported high patient satisfaction with multidisciplinary shared medical appointments for alopecia areata and frontal fibrosing alopecia, with participants appreciating the educational and supportive group environment.
23 citations
,
May 2017 in “Journal of the American Academy of Dermatology” This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.
January 2013 in “Scholarworks (University of Massachusetts Amherst)” This dissertation reveals that FERONIA, a cell wall-binding receptor kinase, plays a crucial role in regulating plant functions such as sugar signaling, pollen tube reception, and RAC/ROP-mediated auxin signaling.
20 citations
,
January 2014 in “Journal of the European Academy of Dermatology and Venereology” This article includes no new results; it discusses ongoing treatment approaches for frontal fibrosing alopecia and lichen planopilaris.
13 citations
,
March 2020 in “Genes” This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.
January 2024 in “The Egyptian Journal of Hospital Medicine” This study found that A-FABP serum levels were significantly higher in male patients with androgenetic alopecia compared to controls, and the authors concluded that A-FABP could serve as a biomarker for early detection of this condition.
December 2025 in “JEADV Clinical Practice” This case study reports on a 72-year-old woman with frontal fibrosing alopecia and hair repigmentation, suggesting the rare occurrence of canities reversal could aid in diagnosing FFA.
9 citations
,
July 2019 in “Dermatologic therapy” In this case report, a patient with frontal fibrosing alopecia and lichen planus responded well to treatment with alitretinoin, suggesting a potential therapeutic role for alitretinoin in similar cases.
March 2025 in “Revista Foco” This review describes the clinical signs, symptoms, and diagnostic findings for alopecia frontal fibrosante, emphasizing the importance of early diagnosis and variable treatment options, and reports no new findings.
2 citations
,
March 2016 in “The Journal of Dermatology” The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).
9 citations
,
October 2019 in “Dermatologic Therapy” This study observed that oral tofacitinib was reasonably well-tolerated but had limited efficacy in treating alopecia areata, with a clinical response seen in 41.4% of patients over six months.
16 citations
,
January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This case study discusses a postmenopausal woman's frontal fibrosing alopecia and lichen planus pigmentosus, controlled with corticosteroids and finasteride, highlighting diagnostic and therapeutic challenges in scarring alopecia.
January 2025 in “Journal of Food Biochemistry” In this study, 2′‐Fucosyllactose (2′‐FL) administration significantly reduced hair loss and increased hair length and thickness in a testosterone-induced androgenic alopecia mouse model, suggesting potential as a therapeutic agent for AGA.
April 2022 in “JAAD International” This study suggests that vitamin D deficiency is likely not involved in the development of frontal fibrosing alopecia, as patients showed similar vitamin D levels to those with female pattern hair loss.
13 citations
,
January 2019 in “Skin appendage disorders” This study reported that fibrosing alopecia in a pattern distribution can occur in patients of color, with clinical and histopathological features allowing for an accurate differential diagnosis.
17 citations
,
July 2022 in “BMC Genomics” This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.
January 2007 in “Frontiers in Medicine” This study found that tofacitinib was an effective and better-tolerated treatment for moderate-to-severe AA compared to SCs, though its efficacy decreased in patients with disease episodes longer than two years.
1 citations
,
February 2024 in “Journal of the European Academy of Dermatology and Venereology” Certain genetic factors may contribute to frontal fibrosing alopecia in Brazil.
May 2024 in “JAMA Dermatology” In this study, researchers identified genetic factors associated with frontal fibrosing alopecia, noting a protective effect of a specific CYP1B1 gene variant, which may offer insights into the disease's pathogenesis and future risk mitigation strategies.
8 citations
,
February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
2 citations
,
July 2020 in “Giornale italiano di dermatologia e venereologia” A woman with frontal fibrosing alopecia experienced unusual hair growth after using a specific topical lotion.
24 citations
,
March 2017 in “Journal of The European Academy of Dermatology and Venereology” This study reported a significant increase in the reporting of sexual dysfunction associated with finasteride use, especially in individuals aged 31-45.
2 citations
,
October 2017 in “Journal of The American Academy of Dermatology” In this study, focal atrichia was associated with late-onset female pattern hair loss, providing a clinical clue to its diagnosis, particularly separating it from other hair disorders.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
134 citations
,
June 2012 in “International Journal of Oral and Maxillofacial Surgery” This article discusses current methods in facial feminization surgery for transsexual women and reports no new clinical results, focusing instead on various surgical techniques used to feminize facial features.