Case Reports
July 2004
in “
JDDG Journal der Deutschen Dermatologischen Gesellschaft
”
TLDR Frontal fibrosing alopecia in postmenopausal women can be managed with early treatment using corticosteroids to stop hair loss.
Frontal fibrosing alopecia (FFA) was described as a rare, slowly progressing form of cicatricial alopecia primarily affecting postmenopausal women, considered a variant of lichen planopilaris. The document detailed two cases of postmenopausal women who developed asymptomatic atrophic alopecia at the frontal hairline over 11 and 24 months. Diagnosis was confirmed through biopsy, revealing perifollicular lymphocytic infiltrate with fibrosis. Treatment with topical corticosteroids, and in one case combined with minoxidil, halted hair loss over 3 months. Although treatment of FFA was challenging, the condition often resolved spontaneously over several years. Early intervention with immunomodulators like corticosteroids and calcineurin antagonists was recommended to arrest the disease during its inflammatory phase.