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This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

This review compiles information on traditional uses, phytoconstituents, and biological activities of Eclipta prostrata but reports no new experimental results; the authors call for more studies to understand its pharmacological mechanisms.

This study developed a multifunctional core-shell fiber dressing that preserves platelet-rich plasma for 180 days, facilitating sustained growth factor release and improved wound healing.

This study found that microneedles containing magnetic intracellular vesicles and tremella polysaccharide improved the hair microenvironment and accelerated hair regeneration in mice with androgenic alopecia.

In this review, skin changes like hair loss and brittle nails linked to nutritional deficiencies common in eating disorders are examined as critical diagnostic tools, highlighting the need for integrated care involving dermatologists, psychiatrists, and nutritionists for effective management.

This study found that in beagles with benign prostate hyperplasia, finasteride treatment increased blood volume and decreased vessel leakiness in the prostate's parenchymal zone as shown by dynamic contrast-enhanced MRI.

This study suggests that Isaria cicadae Miquel rice fermentation extract may enhance regenerative wound healing of hair follicles in mouse skin through the Hippo pathway mechanism.

This study developed a new competitive 5alpha-reductase inhibitor with an IC(50) of 0.84 microM using a novel chemical structure.

This study found that deferiprone significantly reduced dermal fibrosis and skin thickness in mice with chronic kidney disease treated with Omniscan, suggesting iron's role in gadolinium chelate toxicity and nephrogenic systemic fibrosis.

This study used novel methods to detect and map iodine concentrations in pig skin, finding iodine present in the coating, stratum corneum, and tissue around hair follicles.

This study found that heat-killed Enterococcus faecalis EF-2001 promoted hair regrowth in mice, likely by increasing the expression of growth factors and marker genes.

The researchers reported that the aqueous extract of Urtica fissa E.Pritz inhibited 5α-reductase activity in vitro.

This study found that in participants with notalgia paresthetica, 8 weeks of treatment with difelikefalin significantly improved itch intensity and increased the rate of strict complete response compared to placebo, starting as early as week 3.

This study found that chronic administration of testosterone in mice induced an elevated EPO secretion response, possibly mediated through DHT, without affecting baseline EPO levels.

This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.

In this study, the authors reported that AtRXR3, a phosphorus-inducible DUF506 protein, modulates root hair growth under phosphorus stress by interacting with calmodulin and influencing calcium oscillations.

This review discusses the therapeutic potential and safety of bioidentical recombinant human epidermal growth factor (rhEGF) for various skin and mucosa conditions and reports no new clinical results.

This study reports that ZD1839 (Iressa), an anticancer drug, was associated with acneiform eruptions and hair growth abnormalities due to its inhibition of epidermal growth factor receptor signaling in the skin.

The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.

This study demonstrated that Reverse Protein Engineering can decrease the size of Firefly Luciferase from 550 to less than 80 amino acids, but further research is needed to ensure these smaller peptides retain bioluminescent activity.

This study found that local application of nano-liposome-bound EGF at 333.3μg/ml postponed hair growth in rats, unlike lower concentrations or free form.

This study found that ferulic acid significantly reduced seizure susceptibility and depression-like behaviors in a mouse model of catamenial epilepsy, likely by restoring hormone levels and neurotransmitter activity.

In this animal study, exposure to 150 kHz electromagnetic radiation significantly reduced the number and size of follicular cysts in rats with estradiol valerate-induced polycystic ovaries.

This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.

This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.

This study developed two sensitive spectrophotometric methods to accurately determine finasteride in pure and tablet forms, demonstrating linear response and compliance with ICH guidelines.

This study found that carbon dots derived from fucoidan effectively inhibit Enterococcus faecalis and its biofilm, offering a promising approach for managing biofilm-associated persistent endodontic infections.