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This study found that fluconazole increased water transport in renal cells via effects on aquaporin-2 channels, suggesting potential as a treatment for nephrogenic diabetes insipidus, though clinical trials are needed to confirm efficacy in humans.

In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.

This study reports a new industrial process for making finasteride using novel protective groups, demonstrated through spectral data of newly prepared compounds.

This article reviews 12 newly approved drugs with pediatric indications from 2001, discussing their clinical importance for general pediatricians, but reports no new clinical results.

This study concluded that macrophage iron retention due to Ferroportin inactivation hinders skin wound healing but does not affect liver damage or fibrogenesis in a mouse model.

In this study, androgen deprivation, particularly through finasteride treatment, effectively reduced chronic bacterial prostatitis severity in rats, suggesting potential for improved treatment modalities combining finasteride and levofloxacin.

In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.

Finasteride 5mg/day improves hair loss in normoandrogenic Asian women.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

This study found that cepharanthine may be a promising treatment for enterovirus infections, as it offered full protection to mice against lethal EV71 challenges and reduced viral titers and pathology.

This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.

In this research, SEU-302, a newly developed covalent organic framework, exhibited significant antibacterial and wound-healing properties in vitro and in vivo, effectively eliminating Staphylococcus aureus and reducing inflammation under light activation, thereby showcasing its potential for therapeutic photodynamic applications.

This study identified pantolactam based compounds as effective topical antagonists of the androgen receptor, reducing sebum components in a hamster model.

In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.

This study found that a lipid nanoemulsion-based gel of finasteride for topical use improved hair growth and was effective against alopecia, with slow skin permeation and increased efficacy compared to a testosterone-treated group.

This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.

Clofazimine may be effective for treating ashy dermatosis.

This study found that clove oil and LPGSE pretreatment increased finasteride skin permeability, while extending urea pretreatment reduced its penetration.

This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.

This study reports that drug repurposing for COVID-19 has had mixed results, with success for some drugs but a lack of clinical efficacy for others, highlighting the need for improved preclinical profiling and a standardized drug development platform for future antiviral treatments.

This case report highlights the growing trend of adolescents using Finasteride off-label for early hair loss, driven by online misinformation and psychological distress, despite potential side effects and hormonal concerns.

This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.

This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.

This study found that the dissolution profiles of different finasteride polymorphs may affect the quality of finasteride capsules, highlighting the need for polymorphic quality control.

This study found that dabrafenib was well tolerated and led to durable responses in patients with BRAF-mutant differentiated thyroid carcinoma, with a median progression-free survival of 11.3 months.