9 citations
,
March 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the maintenance and morphogenesis of skin appendages rely on both the dose and duration of ectodysplasin signaling.
70 citations
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January 2014 in “International review of cell and molecular biology” This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that adipose-derived stem cell exosomes increased dermal papilla cell proliferation and elevated proteins linked to hair follicle inducibility in vitro.
January 2003 in “Jiefangjun yixue zazhi” In this study, the researchers observed that the expression of certain growth factors and their receptors increases with gestational age, implying a role in skin development, structure maintenance, and wound healing.
18 citations
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December 2024 in “Journal of Drugs in Dermatology” In this literature review, exosomes show promise in cosmetic dermatology for skin rejuvenation and hair restoration; however, challenges like inconsistent isolation methods and lack of FDA approval necessitate further clinical trials to ensure long-term safety and efficacy.
2 citations
,
January 2017 in “Skin appendage disorders” This study found that the prevalence of the exogen phase was negligible in women with androgenetic alopecia and telogen effluvium, with exogen accounting for a small percentage of hair in both conditions.
June 2025 in “IntechOpen eBooks” This chapter highlights the potential of exosomes as innovative agents in cosmetic dermatology, noting their ability to promote skin rejuvenation and target issues like wrinkles, photoaging, and hair loss.
July 2021 in “British Journal of Dermatology” This report describes a boy with ectodermal dysplasias who was genetically diagnosed due to newly discovered TSPEAR gene variants, which have now been associated with this condition.
January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
March 2026 in “Journal of Drugs in Dermatology” This study conducted a review of clinical studies from 2020 to 2025 on exosome-based dermatologic therapies, reporting improvements in skin conditions like wrinkles and scars, though with noted limitations such as small sample sizes and potential conflicts of interest.
7 citations
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August 2023 in “Life” This review discusses using extracellular vesicles as less invasive surrogates for assessing drug-metabolizing enzymes and transporters, suggesting potential advancements in precision therapy, but reports no new clinical results.
This article provides guidance on evaluating information from package inserts and warns that external references or websites may change over time; it reports no new research findings.
5 citations
,
August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.
I cannot provide a conclusion without the content of the document.
1 citations
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June 2019 in “Current developments in nutrition” This case study reports that pancreatic enzyme replacement and fatty acid supplementation improved symptoms of fat malabsorption and essential fatty acid deficiency in a patient with EDS-4.
3 citations
,
April 2019 in “Stem cells international” This study found that CRABP1, Nestin, and Ephrin B2 are expressed in both the tumor stroma and invasive front of skin adnexal tumors and basal cell carcinomas.
14 citations
,
March 2006 in “TSpace” This archive discusses the history and purpose of the Bioline International platform for disseminating scholarly research from developing countries, but reports no new research findings.
March 2026 in “Plastic and Aesthetic Research” This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.
90 citations
,
July 2020 in “Stem Cell Research & Therapy” This study found that adipose-derived stem cell extracellular vesicles reduced wrinkles and promoted cell proliferation in UVB-induced photoaging in mice by decreasing oxidative stress and inflammation.
1 citations
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February 2024 in “ACS applied bio materials” In a rat skin wound model, this study observed that a composite dressing using chitosan hydrogel and exosomes derived from adipose mesenchymal stem cells enhanced wound healing by promoting collagen deposition, angiogenesis, and regeneration of hair follicle structures.
3 citations
,
December 2020 This study investigated the interdigital glands in sheep, highlighting their apocrine sweat glands' ultrastructural characteristics and positive lectin reaction, but reported no new clinical results.
December 2019 in “Thèses en ligne de l'Université Toulouse III (Université Toulouse III)” This study found that the expression of the protein SOX2 is associated with the potential for beige adipocyte formation and adipocyte plasticity in both human and mouse models.
December 2022 in “Scientific Reports” This study found that caffeic acid amide derivative, compound 4, effectively inhibited steroid 5α-reductase type 1 in vitro, suggesting potential for development as a treatment for androgenic alopecia.
January 2017 in “Journal of Chemical Biological and Physical Sciences” This study found that human hair keratin genes contain a few simple sequence repeats, with one repeat in the exon of KRT31 and additional repeats in introns, varying in length compared to their orthologues.
7 citations
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June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
14 citations
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September 2024 in “Cosmetics” This narrative review explores how exosomes and cell culture-conditioned media are becoming key players in the cosmetic industry for skin rejuvenation and prejuvenation, emphasizing their multifunctional topical benefits and potential future applications.
22 citations
,
November 2014 in “Proteins Structure Function and Bioinformatics” In this study, researchers mapped cysteine accessibility in wool keratins and KAPs, revealing that certain cysteines in keratin end domains and Types I and II rod domains are accessible and likely involved in forming disulfide bonds.
The abstract does not report specific results but discusses cosmeceuticals in aesthetic dermatology, addressing myths, regulatory issues, and various compounds used for skin care.
This subject index from the book "Stem Cells in Toxicology and Medicine" offers no new research results.
March 2024 in “Indian Journal of Dermatology/Indian journal of dermatology” This review discusses the potential of exosomes as cell-free treatments for skin aging and various dermatological diseases, highlighting their role in preventing scarring and promoting wound healing, while acknowledging the need for further research and quality control methodologies.