The Effect of Adipose-Derived Stem Cell Exosomes on the Biological Activity of Dermal Papilla Cells

April 2022 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”

Tang Xin, Cuixiang CAO, Yunxiao Liang, Min Liu, Miao-Jian Wan, Tang Xin, Cuixiang CAO, Yunxiao Liang, Min Liu, Miao-Jian Wan

adipose-derived stem cell exosomes dermal papilla cells hair growth cell proliferation Versican alkaline phosphatase hair follicle inducibility ADSC-Exos DPCs

TLDR Adipose-derived stem cell exosomes can boost hair growth by enhancing dermal papilla cell activity.

The study investigated the effects of adipose-derived stem cell exosomes (ADSC-Exos) on dermal papilla cells (DPCs) and hair growth. ADSC-Exos were isolated and co-cultured with DPCs, and their impact on cell proliferation and inducibility was assessed using cell proliferation assays and Western blot analysis. The results showed that ADSC-Exos significantly increased the viability of DPCs and elevated the expression levels of Versican and alkaline phosphatase, indicating enhanced hair follicle inducibility. The study concluded that ADSC-Exos could promote DPC proliferation and improve their ability to induce hair follicle growth.

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