305 citations
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December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
96 citations
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September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
11 citations
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March 2023 in “Stem Cell Research & Therapy” In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.
March 2024 in “Indian Journal of Dermatology/Indian journal of dermatology” This review discusses the potential of exosomes as cell-free treatments for skin aging and various dermatological diseases, highlighting their role in preventing scarring and promoting wound healing, while acknowledging the need for further research and quality control methodologies.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
July 2023 in “International journal of trichology” This case study presents a reversal of hair loss in discoid lupus erythematosus using newer treatments like injectable platelet-rich fibrin.
February 2025 in “Advanced Composites and Hybrid Materials” This study reported that in animal studies of androgenetic alopecia, a biodegradable microneedle patch releasing glutamic acid promoted hair regeneration more effectively than daily minoxidil, with higher hair follicle counts and less frequent dosing, showing the potential for clinical application.
July 2021 in “IntechOpen eBooks” This review discusses the potential of ginseng and its metabolites for treating hair loss and reports no new clinical findings.
October 2025 in “International Journal of Molecular Sciences” This study identified changes in immune activation, ferroptosis, and structural genes in alopecia areata subtypes, suggesting molecular markers that might help understand disease variability and guide future treatments.
October 2021 in “The Egyptian Journal of Hospital Medicine” This article discusses the characteristics of alopecia areata, including its reversible hair loss pattern and uncertain causes, but reports no new clinical findings.
16 citations
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July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
11 citations
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May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
March 2026 in “Plastic and Aesthetic Research” This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.
October 2023 in “International journal of science and research” In a case study, Ayurvedic treatments of leech therapy and topical application of Jayapala beej churna reportedly addressed dosha imbalances associated with Indralupta (Alopecia areata), resulting in new hair growth after several sessions.
61 citations
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January 2018 in “Cosmetics” This review highlights the potential of coffee silverskin's bioactive compounds in combating skin aging and related conditions, suggesting it as a promising natural ingredient for cosmetics due to its antioxidant, anti-inflammatory, and anti-aging properties.
15 citations
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October 2017 in “Clinics in Dermatology” This article reviews risk factors and warning signs of elder abuse in different settings, emphasizing the importance of dermatologists in correctly identifying potential abuse injuries, but presents no new clinical findings.
January 2023 in “Book of Abstracts” COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
2 citations
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January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
5 citations
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April 2022 in “Frontiers in Medicine” This study summarizes the signaling molecules and extracellular components involved in epithelial–mesenchymal interactions, enhancing our understanding of hair follicle regeneration and skin wound healing, but reports no new experimental results.
1 citations
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July 2025 in “Advanced Science” This study developed multifunctional microneedle patches with CTB nanozymes that successfully eradicated MRSA infections in wounds by combining near-infrared laser-induced nitric oxide release and local hyperthermia, while also regulating oxidative stress, inflammation, and angiogenesis through specific signaling pathways.
12 citations
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August 2022 in “Journal of Controlled Release” In this study, a microneedle patch containing conditioned media from hypoxia-pretreated stem cells enhanced hair regeneration in an androgenetic alopecia mouse model by boosting perifollicular vascularization and hair follicle stem cell activation compared to minoxidil.
April 2024 in “Cosmetics” This review highlights the use of microneedling devices and patches to deliver cosmetic agents through the skin, noting their applications in skin rejuvenation and safety considerations such as potential skin irritation and infection.
October 2025 in “Cell Transplantation” This review discusses recent advancements in hair loss treatments, including stem cell and hair follicle cell therapies, growth factors, extracellular vesicles, gene therapy, and tissue engineering, highlighting their potential in improving hair regeneration and follicle health.
1 citations
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December 2025 in “Journal of Pharmacology and Experimental Therapeutics” Exosomes show promise in improving skin health and appearance.
January 2025 in “Cosmetics” This review highlights the multifunctional role of exosomes in dermatology, noting their potential as therapeutic agents for conditions like skin cancers and hair disorders, while also indicating pathogens exploit them for immune evasion.
1 citations
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June 2023 in “Journal of Cosmetic Dermatology” This study found that while clinical evidence is limited, early preclinical results suggest exosome treatment may enhance hair growth and warrant further research for therapeutic use in alopecia.
13 citations
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January 2024 in “Journal of Nanobiotechnology” This research reported that a newly developed adhesive wound dressing (SIS/PAA/LAP) demonstrated higher tissue adhesion and burst strength compared to conventional products, and improved tissue repair outcomes in animal models, suggesting potential for enhanced wound healing applications.
6 citations
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April 2023 in “Cosmetics” In this review, researchers explored the potential of exosomes in cosmetics, skincare, tissue regeneration, and dermatological treatment, noting their promising ability to modulate cellular environments, potentially improving skin health and treating various skin conditions.