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In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.

This review discusses recent advances in using extracellular vesicles as a potential treatment for alopecia and highlights ongoing challenges in their clinical application and mass production; no new clinical results are reported.

This study evaluated the safety and efficacy of Bio-Pulsed avian mesenchymal stem cell-derived small extracellular vesicles when applied topically, finding significant improvements in hair growth, skin rejuvenation, and regenerative microRNA presence among 60 human participants without adverse events.

This study investigated the extracellular polysaccharides from the edible green alga Parachlorella sp. BX1.5, finding that they have potential applications in cosmetics and health products due to their stability, antioxidant properties, and effects on hair growth in mice.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.

This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.

This study found that Ginger-Derived Extracellular Vesicles (GDEVs) may promote hair growth and reduce inflammation in an alopecia mouse model.

This study by Bansaccal et al. found that skin with higher levels of type I collagen density and elasticity in the dermis can inhibit basal cell carcinoma development and spread by acting as a natural barrier against cell reprogramming in mice.

This literature review reports that mesenchymal stem cell-derived secretome, including conditioned medium and extracellular vesicles, shows promise as an effective treatment for various diseases in animal and human in-vivo models, with ongoing clinical trials and recommendations for future research discussed.

This review discusses the applications and potential of microneedles loaded with extracellular vesicles for tissue regenerative repair and disease diagnosis, but does not report new experimental findings.

This study suggests that extracellular vesicles from prostate cancer cells could aid in identifying tumor heterogeneity and serve as biomarkers, while also playing a role in SARS-CoV-2 infection in nasopharyngeal mucus.

This study found that nanovesicles derived from ReNcell VM cells promoted hair growth in mice by activating the Wnt/β-catenin signaling pathway, suggesting they may serve as an alternative to extracellular vesicles for hair growth therapy.

This mini review discusses cellular plasticity in cutaneous wound healing and reports no clinical results; the authors aim to enhance regenerative medicine by examining underlying mechanisms.

This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.

New materials and methods could improve skin healing and reduce scarring.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

In this study, intradermal injections of extracellular vesicles over six months were reported to be safe and effective in improving hair growth among patients with pattern hair loss, with favorable response linked to specific patient factors and treatment volumes.

This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.

This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.

This review discusses what is known about the pathobiology of frontal fibrosing alopecia and reports no new clinical findings, highlighting potential environmental and genetic factors in disease pathogenesis.

This study found that a cocktail of three proteins from embryonic skin can enable adult fibroblasts to regenerate hair follicles by altering gene expression and activating regenerative signaling pathways.

This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.

This review discusses updates in the genetics and clinical understanding of congenital ichthyosis and highlights the addition of N-acetylcysteine and topical enzyme replacement to the treatment options, without providing new clinical results.

This study found that a key gene signature, including FGF11, highlights the immunologic nature of keloid lesions, distinguishing them from normal fibroblasts and scars.

This integrative literature review revealed that chronic stress, characterized by elevated cortisol levels, negatively impacts hair follicle integrity and contributes to alopecia by promoting the premature transition from the growth phase to the resting phase of the hair cycle.

In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.

This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.

In this study, early prenatal treatment with Minoxidil, a lysyl hydroxylase inhibitor, partly improved cardiac outflow tract septation in Tbx1 mutant mice, suggesting that inhibiting collagen cross-linking may mitigate some effects of Tbx1 mutation associated with DiGeorge syndrome.

This review discusses recent research on exosomes' role in dermatology, highlighting their involvement in skin diseases and rejuvenation and exploring therapeutic possibilities in these areas.

This historical review discusses the ancient Egyptians' advanced wound-healing techniques, including the use of honey and moldy bread, and reports no new clinical results.