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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

Hair cortisol is a reliable marker of long-term cortisol levels and is linked to daytime saliva cortisol but not morning levels.

Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

Androgen use may increase the risk of stroke, but more research is needed.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

PAI-2 helps in the maturation and protection of hair and nail cells.

The vitamin D receptor can work without its usual activating molecule.

The right amount of retinoic acid is essential for normal hair growth and development.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.

Balding men had lower bone density, while balding women had higher hip bone density.

Gut microbes significantly affect brain steroid levels.

Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.