Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that finasteride delivered through dissolving microneedles enhanced skin drug permeation compared to films, suggesting potential for improved androgenetic alopecia treatment with fewer side effects.

In this experimental study on alopecia mice, PRP-exosome treatment was reported to significantly improve hair follicle density and the anagen:telogen ratio compared to 5% minoxidil.

This abstract contains no research results; it provides information about the JAMA Dermatology journal and its access options.

This study found that finasteride-loaded nanostructured lipid carriers developed for topical application showed satisfactory size, stability, and prolonged drug release, suggesting potential for enhanced delivery in androgenic alopecia treatment.

This study found that preparing finasteride as a nanosuspension increased its aqueous solubility by more than 2.5 times, potentially enhancing drug bioavailability.

This study found that combining Flutamide and an LHRH agonist in adult male rats effectively inhibited prostatic growth and reduced androgen-sensitive prostatic activity markers to levels similar to castrated rats.

This case report highlights a rare instance of minoxidil-induced pleuro-pericardial effusion with tamponade in a patient with end-stage renal disease on hemodialysis, which improved following pericardiocentesis and discontinuation of the drug.

In this chicken embryo study, E40 hemp seed callus-derived exosomes counteracted DHT-induced inhibition of hair follicle development, suggesting potential for alopecia treatment and hair follicle regeneration.

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

In this case report, a female patient with frontal fibrosing alopecia and lichen scleroatrophicus vulvae experienced excellent results from hair microtransplants combined with finasteride and topical minoxidil, maintained over six years.

In this study, otitis externa in toy poodles and miniature dachshunds was successfully treated using a video otoscope alongside systemic antibiotics and antifungals, with all dogs recovering fully.

This study reports that androgenetic alopecia, the most common form of hair loss affecting both men and women, impacts 50% of the population by age 50.

This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.

This study found that low frequency sonophoresis may reduce percutaneous absorption of sodium fluorescein-loaded liposomes by partially blocking follicular pathways in the skin.

This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.

This mini-review reports that advances in microbioreactor technology, particularly with microfluidics, significantly enhance eukaryotic cell-based biomedicine by improving productivity, scalability, and reproducibility in applications like CAR T-cell manufacturing and organoid growth, though challenges in scalability and material selection remain.

In this study, researchers developed a hierarchically engineered microreactor that effectively combats infected wounds by releasing antimicrobials at acidic sites, eradicating MRSA while avoiding resistance, and enhancing tissue repair through immune system modulation.

This study found that Sonirid Duo, a combination of tamsulosin and finasteride, significantly improved symptoms and quality of life in patients with BPH over 12 months.

This study found that long-term administration of tamsulosin hydrochloride 0.2 mg is effective, safe, and well-tolerated for improving symptoms and quality of life in patients with LUTS of BPH.

This study suggests that exosomes from dermal papilla cells can regulate hair follicle stem cell proliferation via the Wnt3a/β-catenin signaling pathway, potentially informing treatment for human hair problems.

In this case study, a 62-year-old male with a history of uncontrolled diabetes and chronic kidney disease was diagnosed with perforating folliculitis after presenting with dark, raised, pruritic lesions on his limbs, confirmed by histopathological examination showing collagen extruding into hair follicles.

This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.

This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.

In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.

This study found that finasteride-loaded liposomal formulations achieved significantly higher skin permeation and deposition compared to conventional gels and solutions, suggesting potential for effective topical application.

This study describes a novel FUE device that may perform successfully across various patient scenarios, adapting to differences in skin firmness, thickness, and hair curliness.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.