July 2024 in “International Journal of Molecular Sciences” Hemp seed biomaterials may reduce hair loss and improve hair growth.
January 2023 in “International Journal of Trichology” In a case series, this study reported significant hair regrowth in both men and women with androgenetic alopecia using a topical hemp extract high in CBD, THCV, and CBDV over six months.
86 citations
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July 2020 in “International Journal of Molecular Sciences” This review discusses the role of Wnt/β-catenin signaling in hair follicle regeneration and highlights recent progress in developing hair loss treatments targeting this pathway, but reports no new clinical results.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
85 citations
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October 2006 in “Current opinion in cell biology” This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
58 citations
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January 2006 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.
147 citations
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October 2004 in “Experimental dermatology” This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.
581 citations
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October 1998 in “Journal of The American Academy of Dermatology” In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.
227 citations
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January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.