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This study reviews evidence that in keloid development, transforming growth factor-β (TGF-β) drives fibroblast proliferation and fibrosis not only through the classical Smad-dependent pathway but also via equally important Smad-independent signaling cascades, suggesting these pathways as possible targets for more effective keloid therapies.

This review examines current evidence on personalized management strategies for PCOS, but does not present new clinical results; the authors advocate for treatments tailored to predominant symptoms and individual health profiles.

This review presents evidence supporting acupuncture's potential benefits for AA treatment but notes the findings are limited by low-quality evidence and small sample sizes, suggesting a need for future large-scale, rigorous studies.

This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.

This review synthesizes evidence that photobiomodulation may provide robust symptomatic relief for knee osteoarthritis but indicates its potential for structural regeneration remains speculative and needs further long-term validation.

This review highlights current evidence showing that hormonal changes significantly influence skin aging, with estrogen decline during menopause having a major impact on women's skin health, while testosterone decreases contribute to aging in men.

This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.

This study reviewed evidence on injectable regenerative treatments for female pattern hair loss, finding that while PRP consistently improves hair density and thickness, the impact of such treatments on psychological wellbeing remains unclear, and patient-reported outcomes are inconsistently assessed.

This systematic review synthesizes evidence on the distribution of 5a-reductase isozymes and their implications for mental health, finding that inhibition of neurosteroidogenesis may contribute to anxiety, depression, and suicidality, with some patients experiencing persistent psychiatric effects from finasteride or dutasteride.

This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.

This study reviewed evidence suggesting that the loss of dermal white adipose tissue (dWAT) during menopause may be linked to decreased estrogen levels, potentially affecting skin health, and discussed non-hormonal treatments, like magnolol, that might help restore dWAT and improve menopausal skin changes.

This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.

This review synthesizes evidence on how RNA modifications affect wound healing, particularly in skin, bone, and corneal injuries, emphasizing potential therapeutic strategies for burns and trauma in relation to these cellular processes.

This paper reviews the evidence connecting androgen deficiency to skin ageing in men, emphasizing that reduced testosterone exacerbates ageing signs like epidermal thinning and decreased elasticity and advocates for tailored skincare and aesthetics for this demographic.

This review outlines evidence-based strategies for diagnosing pediatric hypopigmented disorders and emphasizes distinguishing vitiligo from self-limiting conditions through a systematic clinical approach; no new results are reported.

This study found that evidence for the efficacy of herbal and traditional treatments for alopecia is varied, with some key positive findings, such as the effectiveness of rosemary oil and pumpkin seed oil in increasing hair count.

This narrative review assesses evidence on the role of oral supplements in reducing common side effects caused by isotretinoin treatment for acne vulgaris, with the aim of providing guidance for enhancing treatment tolerability.

This review synthesizes evidence supporting the efficacy of PRP in dermatological conditions like wound healing and alopecia, but emphasizes the need for standardized protocols and larger randomized controlled trials.

This review consolidates evidence on Croton tiglium's bioactive compounds and effects, discussing its potential uses in treatments like hair-growth formulations, yet emphasizes the significant safety challenges due to the plant's inherent toxicity.

This study reviewed evidence on biologic drugs targeting immune cells for alopecia areata, finding mixed results: some achieved case-level hair regrowth, but controlled trials often showed limited efficacy.

This review compiles evidence indicating that rosemary essential oil may enhance cognitive function, sleep quality, mood, and pain management in aromatherapy; however, it also notes potential allergic reactions, emphasizing caution in its use.

This study found evidence for a genetic basis of polycystic ovary syndrome, indicating an autosomal dominant pattern of inheritance among first-degree relatives.

This review examines the evidence on nutritional and herbal supplements for women's health, emphasizing the need for more long-term studies to develop evidence-based guidelines for personalized supplementation.

This review found preliminary evidence suggesting that photothermal conditioning enhances the bioactivity of platelet-rich plasma, potentially improving hair regeneration outcomes, but highlights the need for standardized protocols and further studies to confirm its efficacy and safety.

This review describes evidence suggesting regular apple consumption may improve cardiovascular health and reduce risks for chronic diseases through antioxidant, anti-inflammatory, and other beneficial effects, particularly when consumed as whole fruits rather than processed forms.

This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.

This review consolidates evidence on 93 plant species used in Zimbabwe for treating 21 skin-related conditions, reporting antimicrobial, anti-inflammatory, and antioxidant properties, though safety data remains inconsistent.

This study highlights conflicting evidence on the safety and efficacy of nutritional supplements for hair loss in breast cancer patients, emphasizing the need for oncologist management and further research.

This review highlights evidence that exercise benefits skin health by enhancing collagen synthesis and reducing oxidative stress and discusses the potential of AI technology to personalize exercise programs, optimizing skin benefits based on individual needs and environmental factors.

This study reviewed evidence on the role of specific genes (FKBP12, SAMAHD1, TRF2, CD155, and GATA3) in predicting how breast cancer patients might respond to adjuvant chemotherapy, aiming to monitor these markers in blood or tissue samples.