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    Epidemiology and Burden of Alopecia Areata in Taiwan: A Systematic Review

    January 2026 in “ Frontiers in Medicine ”
    Chao-Chun Yang, Sheng-Hsiang Ma, Pei Jung Yen … C. Chen
    Studysummary This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.
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    Research cited in this study 28

    1. Taiwanese Dermatological Association Consensus on the Diagnosis and Management of Alopecia Areata Dermatologica Sinica · 2025
    2. Epidemiology, Treatment Patterns, And Healthcare Resource Utilization Study Of Patients With Alopecia Areata In Taiwan's National Health Insurance Research Database Value in Health Regional Issues · 2024
    3. Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis American Journal of Clinical Dermatology · 2023
    4. Alopecia Areata in Latin America: Where Are We and Where Are We Going? Dermatology and Therapy · 2022
    5. Alopecia Areata and Risk of Atopic and Autoimmune Conditions: Population-Based Cohort Study Clinical and Experimental Dermatology · 2022
    6. Prevalence, Comorbidities, and Treatment Patterns of Japanese Patients with Alopecia Areata: A Descriptive Study Using Japan Medical Data Center Claims Database The Journal of Dermatology · 2022
    7. No Increased Risk of Alopecia in Ankylosing Spondylitis Patients: A Population-Based Cohort Study in Taiwan International Journal of Rheumatic Diseases · 2022
    8. Prevalence and Risk Factors Associated with the Occurrence of Autoimmune Diseases in Patients with Alopecia Areata Journal of Inflammation Research · 2021
    9. Alopecia Areata Treatment Patterns, Healthcare Resource Utilization, and Comorbidities in the US Population Using Insurance Claims Advances in Therapy · 2021
    10. The Epidemiology of Alopecia Areata: A Population-Based Cohort Study in UK Primary Care British Journal of Dermatology · 2021
    11. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
    12. Patient Perspectives of the Social, Emotional and Functional Impact of Alopecia Areata: A Systematic Literature Review Dermatology and Therapy · 2021
    13. Treatments for Alopecia Areata: A Systematic Review and Network Meta-Analysis Dermatologic therapy · 2021
    14. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    15. Bidirectional Association Between Alopecia Areata and Migraine: A Nationwide Population-Based Cohort Study Journal of the American Academy of Dermatology · 2020
    16. Association of Sensorineural Hearing Loss in Patients With Alopecia Areata JAMA Dermatology · 2020
    17. Assessment of a Bidirectional Association Between Major Depressive Disorder and Alopecia Areata JAMA Dermatology · 2019
    18. Systemic Treatments for Alopecia Areata: A Systematic Review Australasian journal of dermatology · 2018
    19. Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study Cancer Medicine · 2018
    20. Immune Privilege Collapse And Alopecia Development: Is Stress A Factor Skin Appendage Disorders · 2017
    21. Alopecia Areata: Current Situation and Perspectives Archivos Argentinos De Pediatria · 2017
    22. Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2015
    23. Alopecia Areata Increases the Risk of Stroke: A 3-Year Follow-Up Study Scientific Reports · 2015
    24. Autoimmune Comorbid Diseases Associated with Lichen Planus: A Nationwide Case-Control Study Journal of the European Academy of Dermatology and Venereology · 2014
    25. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    26. Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata Clinical and Developmental Immunology · 2013
    27. Late-Onset Alopecia Areata: A Retrospective Study of 73 Patients from Taiwan Journal of the European Academy of Dermatology and Venereology · 2012
    28. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005