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Transgender and gender-diverse adults on hormone therapy often face drug-hormone interactions, especially with multiple psychotropic medications.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

There is no standardized treatment for hidradenitis suppurativa, and individualized plans are needed.

Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.

PROTO1 and PROTO2 protect against hearing damage.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Women may need different blood pressure guidelines than men for heart disease prevention.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

Adult female acne is complex and requires a combination of treatments for effective management.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Sex hormones affect brain cells differently in males and females.

Compound 3 protects the heart from damage by activating A1-adenosine receptors.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.