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A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

The combination of laser and topical steroids is more effective for treating alopecia areata than topical steroids alone.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

Combination therapy works best for female hair loss, increasing density and thickness.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Fat cells help recruit healing cells and build skin structure during wound healing.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.

Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

The 2940-nm Er: YAG laser combined with medication is a safe and better treatment for male hair loss than medication alone.

The 2940-nm Er: YAG fractional laser may help treat receding frontal hairlines in men with androgenetic alopecia.