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research Transethosomes: A Breakthrough System for Transdermal and Topical Drug Delivery
This review discusses ethanol-based transethosome vesicles for drug delivery through the skin, but reports no new clinical results.
research MICROBIAL OXIDATION OF FINASTERIDE WITH MACROPHOMINA PHASEOLINA(KUCC 730)
This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends
This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.
research Nano-CoCr2O4 Catalysts Promote the Synthesis of Diamino Pyrimidine Oxide Derivatives
In this experiment, CoCr2O4 spinel chromite nanocatalysts showed high catalytic efficiency with a 95.6% yield in producing 4-substituted diaminopyrimidine oxides from 2,6-diamino-4-chloropyrimidine N-oxide, while maintaining stable performance over five reuse cycles.
research Chemical Peels: The Common Channel
This article has no abstract and provides no new results; it is likely a narrative or commentary on chemical peels.
research Finasteride/Minoxidil
research Exosome laden sprayable thermo-sensitive polysaccharide-based hydrogel for enhanced burn wound healing
This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
research Severe cutaneous adverse reactions to drugs
This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
research Erosive pustular dermatosis of the scalp: causes and treatments
This review discusses erosive pustular dermatosis of the scalp, highlighting its wide variety of causes and multiple effective treatment options beyond high-potency topical steroids, and reports no new clinical results.
research Can hair be protected from oxidative damage during and after bleaching
This study assessed three materials—L-arginine, hydrolysed keratin, and cystine-silanol copolymer—ex vivo for their potential to reduce undesirable effects of hair bleaching, such as damage to hair proteins.
research The Double-Edged Sword of Epidermal Growth Factor Receptor Inhibitor: Rash as Toxicity and Prognostic Marker
In this reported case, a 50-year-old man developed an acneiform rash, a common skin side effect of EGFR inhibitor therapy, after starting lapatinib for breast cancer; treatment with doxycycline and hydrocortisone cream led to significant improvement within one week.
research Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
This study identified CYP3A4 as a key isozyme involved in the oxidative metabolism of finasteride in human liver microsomes.
research A novel approach to manage skin toxicity caused by therapeutic agents targeting epidermal growth factor receptor
In this study, a combined therapy of nicotinamide and green tea polyphenols was reported to improve EGFR inhibitor-related skin toxicity and patient quality of life, suggesting it merits further investigation.
research The effect of long‐chain monoenes on prostaglandin E2 synthesis by rat skin
This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.
research Fluorine-Induced Apoptosis and Lipid Peroxidation in Human Hair Follicles In Vitro
research Trans glutaminase-mediated cross-linking in mammalian epidermis
research 14 Dermatological drugs, topical agents, and cosmetics
This chapter reviews dermatological treatments, noting that botulinum toxin A is associated with a higher occurrence of focal weakness compared to controls, and reports on adverse effects of finasteride and PUVA therapy.
research Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report
This report describes the successful resolution of an epidermoid cyst using a minimally invasive approach with intralesional injection of recombinant enzymes.
research Treatment of Exogenous Ochronosis With Advanced Fluorescence Technology
Advanced fluorescence technology effectively treats skin discoloration from certain creams.
research Hydrogen peroxide disrupts scarless fetal wound repair
This study found that hydrogen peroxide interfered with scarless healing in a murine fetal wound repair model, potentially by inducing transforming growth factor-beta1, which may contribute to increased fibrosis.
research Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management
This review discusses the presentation and management of skin toxicity from epidermal growth factor inhibitors, highlighting a correlation between cutaneous adverse effects and tumor response, but reports no new clinical results.
research Topical application of dehydroxymethylepoxyquinomicin improves allergic inflammation via NF-κB inhibition
This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.
research Synthesis and Performance of Potassium Monoester Maleate: A Multifunctional Surfactant Towards Hair Repair
In this study, researchers synthesized new surfactants with hair repair properties, finding that they effectively restored the hydrophobic barrier of damaged hair and improved combing ease compared to untreated hair, highlighting their potential in haircare products.
research Mitoxantrone, Etoposide and Prednisolone—a Novel Combination in The Treatment of Relapsed and Refractory Lymphoma
This study reported a 74% overall response rate for a new combination chemotherapy of mitoxantrone, etoposide, and prednisolone in patients with relapsed or refractory Hodgkin's disease or non-Hodgkin's lymphoma.
research Fixed-Drug Eruption due to Dextromethorphan
This case report details a fixed-drug eruption in a woman linked to the use of dextromethorphan, marking it as a previously unreported skin reaction to this medication.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Acute Localised Exanthematous Pustulosis
This report describes a case of acute localised exanthematous pustulosis in a 19-year-old boy after using amoxicillin-clavulanic acid, with new dermoscopic features identified.
research Pretibial Pruritic Papular Dermatitis: A Case Report and Emphasis on Effective Treatment with Pentoxifylline
This report describes a 60-year-old female with pretibial pruritic papular dermatitis who showed significant improvement of skin lesions after one month of treatment with oral pentoxifylline. The authors highlight the unique clinical and histological features of PPPD and propose pentoxifylline as a potential therapy.
research A combination of low-dose systemic etretinate and topical calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching in Olmsted syndrome associated with a TRPV3 mutation
This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.