14 Dermatological Drugs, Topical Agents, and Cosmetics

    January 2007 in “ Side effects of drugs annual
    Sandra Knowles, Gary Wong, Neil H. Shear
    TLDR Dermatological treatments can have significant side effects, including allergic reactions, sexual dysfunction, and increased cancer risk.
    The document reviewed various dermatological drugs, topical agents, and cosmetics, highlighting their uses and associated adverse effects. Botulinum toxin A was used for facial wrinkles and hyperhidrosis, with about 25% of patients experiencing mild to moderate adverse events. VP-eicosene copolymer served as a waterproofing agent in various applications. Contact allergy to 5-aminolaevulinic acid (ALA) was rare, but a case of acute eczema and hyper-reactivity was noted after photodynamic therapy. Acitretin therapy in a 79-year-old man led to capillary leak syndrome with significant edema and hemorrhagic lesions. The document also mentioned adverse effects of psoralens plus UV-A therapy, including non-melanoma skin cancer and pigmentary disorders.
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