14 Dermatological Drugs, Topical Agents, and Cosmetics

The document reviewed various dermatological drugs, topical agents, and cosmetics, highlighting their uses and associated adverse effects. Botulinum toxin A was used for facial wrinkles and hyperhidrosis, with about 25% of patients experiencing mild to moderate adverse events. VP-eicosene copolymer served as a waterproofing agent in various applications. Contact allergy to 5-aminolaevulinic acid (ALA) was rare, but a case of acute eczema and hyper-reactivity was noted after photodynamic therapy. Acitretin therapy in a 79-year-old man led to capillary leak syndrome with significant edema and hemorrhagic lesions. The document also mentioned adverse effects of psoralens plus UV-A therapy, including non-melanoma skin cancer and pigmentary disorders.