TLDR Dermatological treatments can have significant side effects, including allergic reactions, sexual dysfunction, and increased cancer risk.
The document reviewed various dermatological drugs, topical agents, and cosmetics, highlighting their uses and associated adverse effects. Botulinum toxin A was used for facial wrinkles and hyperhidrosis, with about 25% of patients experiencing mild to moderate adverse events. VP-eicosene copolymer served as a waterproofing agent in various applications. Contact allergy to 5-aminolaevulinic acid (ALA) was rare, but a case of acute eczema and hyper-reactivity was noted after photodynamic therapy. Acitretin therapy in a 79-year-old man led to capillary leak syndrome with significant edema and hemorrhagic lesions. The document also mentioned adverse effects of psoralens plus UV-A therapy, including non-melanoma skin cancer and pigmentary disorders.
44 citations,
July 2004 in “Archives of Dermatology” Finasteride for hair loss has minimal impact on sexual function.
11 citations,
February 2004 in “Clinical and Experimental Ophthalmology” Taking Propecia might lead to the development of cataracts.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
1 citations,
April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.
2 citations,
November 2015 in “Actas Dermo-Sifiliográficas” The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.
4 citations,
January 2018 in “Journal of dermatology & dermatologic surgery” There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.