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The study suggests that nestin-expressing progenitor cells can differentiate into outer root sheath keratinocytes in hair follicles, indicating distinct progenitors for different hair follicle and epidermal components.

Syringomas likely start in the upper dermis and form distinct luminal structures.

This study reports various immunophenotypical patterns in apocrine mixed skin tumors, resembling the structures of hair follicles, sebaceous glands, and apocrine glands.

This article reviews the distinctive features of cutaneous lymphadenoma, a variant of trichoblastoma, and its differential diagnosis, but it presents no new empirical results.

A 90-year-old woman's hand lesion was a rare, aggressive skin cancer treated successfully with surgery.

This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.

This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.

This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.

This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.

This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.

This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.

This case report describes a 29-year-old Japanese man with follicular mucinosis, suggesting nestin-positive, multipotent hair follicle stem cells may be involved in reticular epithelial degeneration of the outer root sheath.

In this study, researchers reported that specific immunoreactivity patterns observed in hair follicle stem cell markers suggest different origins for trichilemmoma, basal cell carcinoma, and squamous cell carcinoma in human skin tissues.

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.

This case report documents only the second known instance of congenital lymphadenoma, expanding the diagnostic possibilities for cutaneous lymphoepithelial tumors in children.

This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.

This article argues that lineage labeling with genetic markers is the gold standard for identifying epithelial stem cells, contrary to the view that in vitro methods alone are sufficient.

This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.

This study demonstrated that the highly divergent WDSV rv-cyclin significantly stimulates eukaryotic cell proliferation, leading to hyperplastic skin lesions in transgenic mice.

In this study, researchers observed that nestin-expressing cells in mice can differentiate into blood-vessel-like and nerve-like structures within human melanoma tumors, while bevacizumab treatment altered the origin of these structures to trans-differentiated melanoma cells without significantly impacting tumor growth.

This study found that the expression of LRIG1 in Merkel cell carcinoma tumors was associated with improved overall and cancer-specific survival.

In this case report, a rare melanotrichoblastoma tumor was identified in a 51-year-old female following the histological and immunohistochemical analysis of a lesion on the pubo-inguinal area, presenting with strong epithelial marker positivity and a low proliferative index.

This study found that GLI1 RNA CISH was highly sensitive and specific for distinguishing basal cell carcinoma from nonfollicular epithelial neoplasms but not from most benign follicular tumors.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

This study reported that Indian hedgehog (Ihh) signaling plays a crucial role in regulating tumor progression and metastasis in epithelial cancers, with Ihh deficiency leading to increased malignancy and metastasis in mice.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.

This study found that the cell of origin in mouse skin affects melanoma phenotype and response to therapies, despite the presence of the same genetic mutations.

This study found that K15 is a useful marker for investigating the role of stem cells in canine hair follicle tumours, while nestin is not optimal.