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Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

Scientists can now create skin with hair by reprogramming cells in wounds.

Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.

Skin varies in thickness, color, and features due to complex genetic and cellular processes.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Autophagy is important for determining the protein makeup of hair.

Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

RANK-RANKL signaling is essential for hair growth and skin health.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

ILK is essential for proper hair follicle development and structure.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Scientists created stem cells that can grow hair and skin.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

HFMs can help study hair growth and test potential hair growth drugs.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.