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Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.

Women with greater androgen sensitivity respond better to finasteride for hair loss.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Key genes can rewire networks, changing skin appendage types.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Men with more vanadium in their blood and who drink less soy milk are more likely to have hair loss.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

DNMT3A is crucial for healthy skin and hair growth.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.