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Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Papain cream removes hair better than papain gel, causing hair follicles to widen and skin to thicken.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Epigenetic mechanisms control skin development by regulating gene expression.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

Hair and nails are skin parts that develop early and serve protective and functional roles.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.