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    Glossary Epidermal Proliferation

    rapid cell division in skin's outermost layer

    Epidermal proliferation refers to the process by which cells in the outermost layer of the skin, known as the epidermis, rapidly divide and multiply. This process is crucial for skin regeneration and repair, helping to replace dead or damaged cells and maintain the skin's protective barrier. In conditions like psoriasis, this proliferation can become excessive, leading to thickened, scaly patches of skin.

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    Research 30 of 1000+

    1. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit Proceedings of the National Academy of Sciences of the United States of America · 2011 · 60 citations
    2. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin Nature Communications · 2018 · 48 citations
    3. Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell? Cell Stem Cell · 2007 · 153 citations
    4. A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes Transgenic Research · 2024 · 1 citations
    5. EVALUATION OF EFFICACY OF FOLLICULAR UNIT EXCISION VERSUS FOLLICULAR UNIT EXCISION WITH NANOFAT IN SCARS IN HAIRY AREAS ALEXMED ePosters · 2025
    6. Nevus Sebaceous Indian Journal of Dermatopathology and Diagnostic Dermatology · 2025
    7. Stem Cells in Nonmelanoma Skin Cancer 2004
    8. Reflection confocal microscope characteristics of rose acne and some thoughts caused by it Skin research and technology · 2022
    9. Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars Australasian journal of dermatology · 2024
    10. In vitro skin models to study epithelial regeneration from the hair follicle PLoS ONE · 2017 · 19 citations
    11. Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells Journal of Cellular Physiology · 2016 · 6 citations
    12. Multi‐tasking epidermal stem cells: Beyond epidermal maintenance Development, Growth & Differentiation · 2018 · 23 citations
    13. Hair Follicle Stem Cells 2003 · 142 citations
    14. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations
    15. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America · 1996 · 154 citations
    16. Urokinase is a Positive Regulator of Epidermal Proliferation In Vivo Journal of Investigative Dermatology · 1999 · 28 citations
    17. Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle Stem Cells · 2010 · 39 citations
    18. RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling PLoS ONE · 2017 · 21 citations
    19. LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy Journal of Investigative Dermatology · 2019
    20. The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model PLoS ONE · 2016 · 16 citations
    21. Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis Frontiers in oncology · 2022 · 13 citations
    22. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    23. Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23 Journal of cosmetic dermatology · 2023
    24. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    25. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations
    26. The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study Journal of Cosmetic Dermatology · 2017 · 12 citations
    27. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    28. Epidermal Stem Cells Cultured on Collagen-Modified Chitin Membrane Induce In Situ Tissue Regeneration of Full-Thickness Skin Defects in Mice PLoS ONE · 2014 · 28 citations
    29. Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts Methods in molecular biology · 2013 · 11 citations
    30. EGF–FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs) Experimental Cell Research · 2014 · 29 citations