70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
78 citations,
August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
27 citations,
June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
8 citations,
March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” The 14-3-3σ gene is essential for preventing hair loss.
November 2022 in “Journal of Investigative Dermatology” Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
138 citations,
June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” CD101 is highly effective in treating dermatophytosis in guinea pigs.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A potential treatment for atopic dermatitis could be to increase PADI1 expression to improve skin barrier function.
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
46 citations,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
April 2023 in “Journal of Investigative Dermatology” PRP can improve hair growth in people with hair loss, but more research is needed.
5 citations,
August 2021 in “Clinics in dermatology” PRP is popular in aesthetic treatments but its effectiveness and safety are still questioned.
October 2021 in “European journal of cancer” Repeated biopsies are crucial for managing lupus panniculitis when initial treatments fail.
September 2019 in “Journal of Investigative Dermatology” Apple stem cell extract may increase the number of stem cells in a part of the hair follicle.
March 2022 in “Ophthalmology Journal” A woman's rare benign eyelid tumor was correctly identified through detailed tissue analysis.
2 citations,
January 2011 in “The Korea Journal of Herbology” Korean medicinal herbs in hair tonic and food increased hair growth in mice.
7 citations,
April 1996 in “Archives of dermatological research” Topical tacalcitol can treat psoriasis by acting directly on skin cells.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
April 2023 in “Journal of Investigative Dermatology” Combining platelet-rich plasma with laser therapy improves treatment for vitiligo, skin rejuvenation, and acne scars, but more research is needed.
55 citations,
January 2020 in “Advances in experimental medicine and biology” Vitamin D and its receptor may help prevent skin cancer.
2 citations,
September 2019 in “Serbian Journal of Dermatology and Venerology” A rare skin condition causing scarring was successfully treated with topical erythromycin and benzoyl peroxide.
14 citations,
September 2018 in “Biochemical and Biophysical Research Communications” Growing hair cells with dermal cells can potentially treat hair loss.
149 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
24 citations,
November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
6 citations,
April 2013 in “Current Dermatology Reports” Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
6 citations,
December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
10 citations,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.