A Rare Primary Subcutaneous Panniculitis-Like T-Cell Lymphoma with Scalp Involvement Associated with Lupus Panniculitis

    October 2021 in “ European journal of cancer ”
    Farah El Hadadi, Line Mezni, Kaoutar Znati, Mariame Meziane, Nadia Ismaïli, Laïla Benzekri, Karima Senouci
    TLDR Repeated biopsies are crucial for managing lupus panniculitis when initial treatments fail.
    A 20-year-old Moroccan female with a history of photosensitivity and lipoatrophic hyperpigmented plaques was diagnosed with a rare primary subcutaneous panniculitis-like T-cell lymphoma (SPTCL) associated with lupus erythematosus panniculitis (LEP) and alopecia areata. Initial treatment with hydroxychloroquine showed no improvement, leading to further biopsies that confirmed the diagnosis. The patient was then treated with oral steroids and topical minoxidil, resulting in the resolution of subcutaneous nodules and regrowth of hair after 4 months. This case highlights the importance of repeated biopsies in managing lupus panniculitis when disease control is not achieved.
    Discuss this study in the Community →