Platelet-Rich Plasma and Laser Combination Therapy in Dermatology: A Systematic Review

    April 2023 in “ Journal of Investigative Dermatology ”
    Simonetta I. Gaumond, R. Abdin, M. Kaiser, J.J. Jimenez
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    collagen →
    Image
    Studysummary This review discusses randomized trials on PRP and laser therapy for vitiligo, acne scars, and skin rejuvenation, finding combination therapy may yield clinical improvements but calls for more diverse studies. Our plain-language summary of this paper — not a Tressless recommendation.
    The systematic review analyzed 11 randomized control trials from 2012 to 2022, investigating the combination of platelet-rich plasma (PRP) and laser therapy for treating vitiligo, skin rejuvenation, and acne scarring. Four studies found that fractional carbon dioxide laser resurfacing combined with PRP was most effective for vitiligo treatment. One study reported improvements in skin elasticity, texture, erythema reduction, and increased collagen density when using fractional laser with PRP for skin rejuvenation. All six studies examining the combination of fractional CO2 laser and PRP for acne scarring showed greater clinical improvement and faster recovery of laser-damaged skin. Despite these promising results, the review calls for more studies with larger sample sizes and diverse skin types to further establish the clinical benefits of combining laser therapy with PRP in dermatology.
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