82 citations,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
64 citations,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
56 citations,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
35 citations,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
25 citations,
April 2021 in “npj Regenerative Medicine” Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
24 citations,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
6 citations,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
3 citations,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
24 citations,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
479 citations,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
132 citations,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
2 citations,
February 2022 in “Human Gene Therapy” Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.
1 citations,
August 2023 in “Gels” The hydrogel with silver and ibuprofen promotes wound healing and fights infection.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
2 citations,
January 2020 in “Evidence-based Complementary and Alternative Medicine” Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.
The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.
6 citations,
November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
April 2018 in “Journal of Investigative Dermatology” The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
September 2016 in “Journal of dermatological science” Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.