research The Skin and Subcutaneous Tissues: Conditions, Diagnosis, and Systemic Implications
The document concludes that skin and nail changes can indicate various underlying health conditions.
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research Autoimmunity in Satoyoshi Disease: A Systematic Review
Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.
research Support for Dermatological Research in Sub-Saharan Africa: Insights from African Hair and Skin Research Programs
The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.
research Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management
Finasteride niosomes were developed and found to be effective in treating hair loss, with better results than commercial minoxidil, and could be a promising topical treatment for hair loss.
research Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Roles of Steroid Receptors in the Lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature
Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research Intrinsic and Extrinsic Factors Associated with Hair Graying and Therapeutic Potential of Plant Extracts and Phytochemicals
Plant extracts may help prevent or reverse hair graying.
research Impact of Androgen Status and Anti-Androgen Therapy on the Course of COVID-19 in Men
Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.
research Patient Satisfaction and Quality of Life Among Adult Women with Androgenetic Alopecia Using 5% Topical Minoxidil
Most women with hair loss using 5% topical Minoxidil are satisfied with the treatment, but hair loss still affects their daily habits and social life.
research Primary Cicatricial Alopecia Among Libyan Patients: A Clinicopathological and Epidemiological Study
Early diagnosis and treatment can reduce cicatricial alopecia in middle-aged individuals, especially females.
research Epidemiological and Biochemical Factors (Serum Ferritin and Vitamin D) Associated with Premature Hair Graying in the Egyptian Population
Low iron levels are linked to premature graying of hair, but vitamin D levels are not.
research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus Epidermidis Clonal Lineages
Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.
research Clinical Description of Frontal Fibrosing Alopecia with Concomitant Lichen Planopilaris
Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.
research Adult Kawasaki Disease: Report of Two Cases and Literature Review
Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.
research Case Series of Familial Frontal Fibrosing Alopecia and a Review of the Literature
Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.
research Testosterone Target Therapy: Focus on Immune Response, Controversies, and Clinical Implications in Patients with COVID-19 Infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Factors Associated with Anti-SARS-CoV-2 IgG Antibody Production in Patients Convalescing from COVID-19
Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.
research Knowledge, Attitude, and Practice Regarding COVID-19 Skin Manifestations Among Doctors Working at Khartoum Dermatology and Venereology Teaching Hospital, 2021
Many doctors lack knowledge about COVID-19 skin symptoms and need better education and guidelines.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Design, Synthesis and Anti-Tumor Evaluation of Novel Thiohydantoin Congeners as Androgen Receptor Antagonists With In Vivo Study
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research SARS-CoV-2 Vaccination in Androgen Sensitive Phenotypes – A Study on Associated Factors for SARS-CoV-2 Vaccination and Its Adverse Effects Among Androgenetic Alopecia and Benign Prostate Hyperplasia Patients
Anti-androgen therapy may boost immunity but increases injection site pain in vaccinated patients.
research Letter to the Editor: Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride use may cause sexual dysfunction; more research needed.
research Hair and Scalp Disorders in Women of African Descent
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
research Epidemiological and Investigative Study of Premature Graying of Hair in Higher Secondary and Pre-University School Children
Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.
research Hair Follicle Characteristics as Early Marker of Type 2 Diabetes
Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.