Factors Associated with Anti-SARS-CoV-2 IgG Antibody Production in Patients Convalescing from COVID-19

January 2021 in “ Journal of infection and chemotherapy ”

Satoshi Kutsuna, Yasufumi Asai, Akira Matsunaga, Noriko Iwamoto, Mari Terada, Yusuke Miyazato, Takato Nakamoto, T. Suzuki, Sho Saito, Mio Endo, Kohei Kanda, Kenji Maeda, Tao Jin, Masayuki Hojo, Yukihito Ishizaka, Norio Ohmagari

TLDR Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.

This study investigated factors influencing anti-SARS-CoV-2 IgG antibody production in 84 COVID-19 patients. It found that male sex (P = 0.04), diabetes mellitus (P = 0.03), and high C-reactive protein levels during the disease course (P < 0.001) were associated with elevated antibody titers. Antibody levels peaked in weeks 5 and 6 after symptom onset, while glucocorticoid use did not affect antibody titers.

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