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Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.

Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Zebrafish with mutations similar to human Cantú Syndrome have heart cells with altered channel properties, making them a good model to study the condition.

Healing of heart and skin wounds in animals are similar.

Human stem cells can help form hair follicles in mice.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Mice with autoimmune hair loss showed signs of heart problems.

Zinc levels and lymphocyte counts might be important in heart disease development.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

Different enzymes are active in different parts of developing mouse organs.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.

Minoxidil may cause heart issues in animals and humans.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Genetic and environmental factors, like smoking and exercise, affect male hair loss.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Skin diseases like psoriasis, lupus, and others can increase heart disease risk due to factors like chronic inflammation and genetic susceptibility.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Skin fat plays a key role in immune defense and healing beyond just storing energy.