8 citations
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February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
August 2015 in “Free Radical Biology and Medicine” This study suggests a potential link between proteasome function and nucleotide excision repair in animal models with defects in the NER pathway, with implications for ageing.
156 citations
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August 2016 in “Journal of controlled release” This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.
66 citations
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December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.
September 2023 in “Deleted Journal” This study observed that lifestyle modifications resulting in weight loss improved menstrual irregularity and hormonal balance among infertile obese women with polycystic ovary syndrome, although changes in total testosterone and estrone were not significant.
136 citations
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March 1996 in “Journal of the American Chemical Society” This study explains finasteride's high potency and specificity as a mechanism-based inhibitor for treating benign prostatic hyperplasia by detailing its interaction with human type 2 steroid 5α-reductase.
102 citations
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August 2008 in “Genes & Development” This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.
49 citations
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October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
48 citations
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July 2009 in “The Journal of Sexual Medicine” In this study, 50 mg/day of DHEA supplementation in postmenopausal women did not significantly improve sexual function compared to a placebo over 26 weeks.
27 citations
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July 2018 in “Experimental dermatology” This study found that autophagy plays a role in sebaceous gland function and sebum composition control in mice lacking the Atg7 gene in keratinocytes.
6 citations
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January 2010 in “Biology and medicine” This study found that chronic use of Russelia equisetiformis extracts in rats may impair liver function, with a more pronounced effect observed from the methanol extract.
5 citations
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December 2015 in “Asian pacific Journal of Tropical Biomedicine” In this study, the aqueous extract from Phthirusa pyrifolia leaves significantly decreased testosterone levels in male Wistar rats without causing liver or kidney damage, suggesting potential effects on libido and reproduction.
2 citations
,
April 2010 in “The Open Dermatology Journal” This review discusses the development and role of corneodesmosin in skin and hair follicle integrity, highlighting findings from mouse models and its connection to genetic diseases, with no new experimental results included.
January 2026 in “American Journal of Translational Research” In this study, the combination of metoprolol and spironolactone in patients with coronary heart disease and heart failure significantly improved cardiac function and reduced inflammation and oxidative stress markers compared to spironolactone alone, with better clinical efficacy and fewer adverse effects.
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.
April 2024 in “The Indonesian Biomedical Journal” This study found that non-vitiliginous melanocyte stem cells from vitiligo patients were unaffected by the disease and could effectively differentiate into melanin-producing melanocytes, suggesting their potential for use in cellular therapy for vitiligo repigmentation.
April 2016 in “Annals of laboratory medicine” The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.
November 2012 in “The Journal of Urology” Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.
74 citations
,
June 2018 in “Cell death and disease” In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.
8 citations
,
January 2021 in “Smart materials in medicine” This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.
3 citations
,
May 2022 in “Oncogene” This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.
1 citations
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March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, a new leave-on hair treatment with Dynagen and zinc salts significantly increased hair growth rate, fibre diameter, and follicle strength in healthy women.
1 citations
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August 2015 in “Current Sexual Health Reports” This review examines the sexual side effects of 5α-reductase inhibitors like finasteride, highlighting the increased risk of erectile dysfunction, libido reduction, and potential contribution to depression without new clinical findings.
December 2018 in “Progress in Medical Sciences” This study observed that methanol extract of Phoenix dactilifera improved kidney function in rats at 4 and 8 mg/kg doses, but a 16 mg/kg dose may impair kidney function by affecting urea and potassium excretion.
277 citations
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July 2002 in “Molecular Endocrinology” In this study, homozygous VDR null mutant mice exhibited nonfunctional vitamin D receptors, leading to growth abnormalities and revealing the limited physiological importance of vitamin D pathways outside the classical receptor.
23 citations
,
September 2015 in “International Journal of Molecular Medicine” This study found that the activation of ER‑β increased keratinocyte proliferation and gene expression related to epidermal regeneration, enhancing wound healing in both cell models and rats.
11 citations
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August 2014 in “Current Urology Reports” This review discusses the known effects of medications for benign prostatic hyperplasia on sexual function and mechanisms of dysfunction but reports no new clinical results.