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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

SHED-CM can reduce hair graying and protect against damage from X-rays.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Graying hair happens due to aging and might be delayed by new treatments.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Targeting NETs may help reduce fibrosis in Crohn's disease.

A patient's gum problems worsened after using cyclosporine for a scalp condition, but improved with a lower dose.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Mice with alopecia areata had wider lymphatic vessels in their skin.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.