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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.

Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.

The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.

Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Skin-derived precursors in hair follicles come from different origins but function similarly.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Small molecule IM boosts hair growth by changing stem cell metabolism.

Exosomes show promise for future tissue regeneration.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

A microneedle patch can help regrow hair by restoring immune balance in hair follicles.

Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.

Creating fully functional artificial skin for chronic wounds is still very challenging.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.