October 2024 in “Cosmetics” In this study, reducing agents like ammonium thioglycolate, L-cysteine, and sodium sulfite in shampoo effectively decreased hair flyaway and frizz without causing damage, as no critical hair damage was observed in structural and tensile strength assessments.
127 citations
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June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
January 2024 in “Indonesian Journal of Pharmaceutical Education” In this experimental laboratory study, three cream formulations containing 1% Caffeine Herbasome® were developed and evaluated for stability, homogeneity, pH, dispersion, and adhesion, with results showing satisfactory stability and suitable adhesion properties for skin application.
4 citations
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January 2017 in “Biological & pharmaceutical bulletin” This study found that inhibiting arachidonate 12-lipoxygenase (ALOX12) may enhance hair cuticle maturation by increasing S100A3 protein citrullination and promoting cuticular differentiation in isolated human hair follicles.
April 2024 in “JMR. Journal of molecular recognition/Journal of molecular recognition” This study found that hydrophilic carbon dots (Lys-CA-CDs) induced bovine serum albumin to form more wormlike fibrils, while inhibiting hen egg white lysozyme from forming hair-like fibrils.
34 citations
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October 1994 in “Journal of Pharmaceutical Sciences” This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.
47 citations
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July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.
182 citations
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December 2021 in “Cosmetics” This literature review discusses recent advances in using essential oils and their components in cosmetic products, highlighting their diverse benefits and challenges in formulation due to varying chemical profiles, as well as addressing safety considerations for these natural ingredients.
2 citations
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January 2015 in “Sen'i Gakkaishi” This study found that washing hair after reduction in a permanent waving process allows for significant reformation of disulfide cross-links, enhancing the strength and elasticity of hair fibers.
8 citations
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January 2009 in “Transactions of the Materials Research Society of Japan” This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.
11 citations
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January 2006 in “Journal of the American Leather Chemists Association” This study investigated multiple alkaline oxidative dehairing systems and found a consistent reaction mechanism for disulfide cleavage across systems, enhancing hair solubilization by enabling structural swelling and water uptake.
The best mix of propylene glycol and sorbitol was found for a cream to prevent hair loss using saw palmetto extract.
7 citations
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May 2021 in “Applied sciences” This study investigated various proteins as eco-friendly hair perming agents for Asian hair and found that bovine serum albumin and keratin achieved perming results comparable to commercial products, while also increasing hair moisture, indicating a protective effect during heat styling.
5 citations
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January 2014 in “Asian Journal of Chemistry” This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.
January 2024 in “Molecules (Basel. Online)” In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.
19 citations
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March 1961 in “Nature” A fatty acid/protein complex in human hair helps protect it from damage.
This study found that encapsulating curcumin within specific polymers increased its oral bioavailability, photostability, and release in both mice and in vitro, compared to free curcumin.
60 citations
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October 2020 in “Journal of Controlled Release” This study found that curcumin nanocrystals efficiently penetrated hair follicles down to the lower infundibulum in an ex-vivo pig ear model, regardless of the gel vehicle used, though passive dermal penetration varied with the vehicle’s skin hydrating properties.
5 citations
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April 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this review, researchers noted that liposomes, due to their ability to stabilize and target drugs, are effective carriers for treating various dermatological conditions such as acne and psoriasis when applied topically.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.
This study explored the formulation of a 1% minoxidil gel shampoo, finding that specific combinations of surfactants significantly affect its foaming ability, which may enhance compliance compared to imported products.
August 2021 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study found that using natural polyphenol cross-linkers like tannic acid and green tea extract during perm treatments improved perming efficiency, wave maintenance, and hair protection compared to a control group.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study found that dexamethasone-loaded polymeric nanoparticles, particularly those combining ethyl cellulose with Eudragit® RS, may improve controlled release and penetration of corticosteroids into the skin and hair follicles compared to traditional methods.
13 citations
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January 2020 in “Nanoscale” Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.
Flubendazole in a nanoemulsion can potentially treat lung cancer and cryptococcal meningitis effectively and safely.
April 2025 in “Digital Commons - East Tennessee State University (East Tennessee State University)” In a mice model of atopic dermatitis, this study reported that a formulated cromolyn sodium oleate gel significantly reduced scab size and provided better healing than dexamethasone, with fewer adverse effects.
August 2026 in “Acta Innovations” This study found that Eclipta alba (L.) Hassk herbal oil formulated with VCO demonstrated enhanced antioxidant, anti-inflammatory, and antibacterial activities, and provided UV protection, with EHO-18 identified as the best-performing version.