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Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

Certain miRNAs are linked to chicken feather development.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.

The TRPV3 gene variant may cause the long-haired suri alpaca coat.

Genes linked to wool fineness in sheep have been identified.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Blocking a specific immune cell signal can trigger hair growth.

The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.

Applying a special compound can promote hair growth without harmful side effects.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Dicer is crucial for hair growth in mice.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Hoxc genes control hair growth through Wnt signaling.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Loss of Fz6 disrupts hair follicle and associated structures' orientation.