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Docetaxel is safe and works well for older people with cancer, with manageable side effects.

Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.

New treatments for hair loss show promise but need more research to confirm safety and effectiveness.

Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Children under 18 had milder SARS with no deaths, but teenagers faced higher severe illness risk, and effective treatments were uncertain.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Topical corticosteroids are the best initial treatment for children's alopecia areata.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

High doses of certain vitamins can cause serious side effects and health risks.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Vorasidenib can cause unusual hair growth.