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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

Nanotechnology improves Clomiphene citrate's effectiveness and reduces side effects for treating ovulatory disorders.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Finasteride may lower cholesterol and slow heart disease progression.

The document discusses how to diagnose and treat conditions like acne, excessive hair growth, and female pattern hair loss related to hormone imbalances.

Surgeons' testosterone levels significantly increase during major head and neck cancer surgeries.

A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

Most women with excessive hair growth in South India have hirsutism without a known cause, with common facial hair growth and some showing hormonal imbalances and polycystic ovaries.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.

A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

PCOS has many symptoms, with high androgen levels being the most common.

Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.

Testosterone therapy increases bone density in older men with low testosterone levels.

Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.