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    Did you mean EGFR inhibitors?
    Glossary EGFR inhibitors

    block cell growth signals to treat certain cancers

    EGFR inhibitors, also known as Epidermal Growth Factor Receptor inhibitors, are a class of drugs that block the activity of the EGFR, a protein on the surface of cells that helps them grow and divide. By inhibiting this receptor, these drugs can slow down or stop the growth of certain types of cancer cells that rely on EGFR for proliferation. They are commonly used in the treatment of cancers such as non-small cell lung cancer and colorectal cancer.

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    Research 30 of 1000+

    1. Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors European journal of cancer · 2007 · 138 citations
    2. Persistent hair growth during treatment with the EGFR inhibitor erlotinib Dermatology Online Journal · 2009 · 39 citations
    3. Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors Supportive Care in Cancer · 2012 · 38 citations
    4. Cutaneous side-effects of EGFR inhibitors and their management. PubMed · 2011 · 38 citations
    5. Erosive Pustular Dermatosis of the Scalp-Like Eruption due to Gefitinib: Case Report and Review of the Literature of Alopecia Associated with EGFR Inhibitors Dermatology · 2012 · 36 citations
    6. The management of EGFR inhibitor adverse events: a case series and treatment paradigm International Journal of Dermatology · 2012 · 32 citations
    7. EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management Oncology and therapy · 2017 · 29 citations
    8. Rash from EGFR inhibitors: Opportunities and challenges for palliation Current Oncology Reports · 2008 · 18 citations
    9. Network pharmacology-based preventive effect of XZF on cutaneous toxicities induced by EGFR inhibitor Biomedicine & Pharmacotherapy · 2020 · 10 citations
    10. EGFR inhibitor-induced folliculitis decalvans: a case series and management guidelines Anti-Cancer Drugs · 2023 · 7 citations
    11. Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers Annals of Dermatology · 2011 · 3 citations
    12. 566 Staphylococcus epidermidis for the topical treatment of epidermal growth factor receptor (EGFR) inhibitor-induced dermal toxicity Journal of Investigative Dermatology · 2024
    13. PRIDE Complex (Papulopustules and/or Paronychia, Regulatory Abnormalities of Hair Growth, Itching, Dryness Due to EGFR Inhibitors) JEADV Clinical Practice · 2025
    14. Folliculitis Decalvans-like Alopecia During Treatment With EGFR Inhibitors for Lung Cancer: A Case Series of 6 Patients Dermatology practical & conceptual · 2023
    15. Síndrome PRIDE: una práctica forma de identificar los efectos adversos cutáneos de los inhibidores del EGFR Revista Medicina Cutánea Ibero-Latino-Americana · 2021
    16. 422 Human hair follicles express PD-L1, whose expression is down-regulated by EGFR and MEK inhibitors ex vivo. A potential mechanism for EGFR inhibitor induced sterile folliculitis Journal of Investigative Dermatology · 2019
    17. MARIO LACOUTURE: How Do I Treat a Patient with Dermatologic Toxicities to EGFR Inhibitors? Oncology times · 2011
    18. Erosive pustular dermatosis of the scalp due to EGFR inhibitors: A multicentric study by EADV task force of ‘Dermatology for Cancer Patients’ Journal of the European Academy of Dermatology and Venereology · 2025
    19. Effets secondaires cutanéo-muqueux des nouvelles molécules anticancéreuses: Inhibiteurs de l'EGF-R, inhibiteurs de tyrosine kinase et stabilisateurs du fuseau mitotique 2011
    20. 861 EGFR/MEK inhibitor therapy induces partial hair follicle immune privilege collapse in vivo and ex vivo Journal of Investigative Dermatology · 2022
    21. The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) syndrome British Journal of Dermatology · 2006 · 90 citations
    22. Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management Dermatology research and practice · 2014 · 68 citations
    23. Nonscarring inflammatory alopecia associated with the epidermal growth factor receptor inhibitor gefitinib Journal of the American Academy of Dermatology · 2006 · 57 citations
    24. EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals Developmental Biology · 2012 · 53 citations
    25. Dermatological side effects of epidermal growth factor receptor inhibitors: ′Pride′ complex Indian Journal of Dermatology · 2014 · 43 citations
    26. A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib Journal of Cutaneous Pathology · 2009 · 33 citations
    27. IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes 2019 · 32 citations
    28. Taiwanese Dermatological Association consensus for the prevention and management of epidermal growth factor receptor tyrosine kinase inhibitor-related skin toxicities Journal of the Formosan Medical Association · 2017 · 22 citations
    29. Treatment of Epidermal Growth Factor Receptor Inhibitor-Induced Acneiform Eruption with Topical Recombinant Human Epidermal Growth Factor Dermatology · 2012 · 19 citations
    30. Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling? Journal of Cellular Physiology · 2008 · 19 citations